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Crossover Designs in Nutrition and Dietetics Research

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Presentation on theme: "Crossover Designs in Nutrition and Dietetics Research"— Presentation transcript:

1 Crossover Designs in Nutrition and Dietetics Research
Jeffrey E. Harris, DrPH, MPH, RD, LDN, Hollie A. Raynor, PhD, RD, LDN  Journal of the Academy of Nutrition and Dietetics  Volume 117, Issue 7, Pages (July 2017) DOI: /j.jand Copyright © 2017 Academy of Nutrition and Dietetics Terms and Conditions

2 Figure 1 A 2×2 crossover design. A or B denotes one of two levels of the independent variable, AB or BA denotes sequence of manipulation of the levels of the independent variable in the crossover design, OA denotes dependent outcome variable measured after manipulation A, OB denotes dependent outcome variable measured after manipulation B, and Washout denotes period of removal of manipulation for specified time interval prior to initiating second manipulation of crossover design. (NOTE: Information from this figure is available online at as part of a PowerPoint presentation.) Journal of the Academy of Nutrition and Dietetics  , DOI: ( /j.jand ) Copyright © 2017 Academy of Nutrition and Dietetics Terms and Conditions

3 Figure 2 A 3×3 crossover design. A, B, or C denotes one of three levels of the independent variable; ABC, BCA, CAB denotes sequence of manipulation of the levels of the independent variable in the crossover design; OA denotes dependent outcome variable measured after manipulation A; OB denotes dependent outcome variable measured after manipulation B; OC denotes dependent variable outcome measured after manipulation C; and Washout denotes period of removal of manipulation for specified time interval before initiating second or third manipulation of crossover design. (NOTE: Information from this figure is available online at as part of a PowerPoint presentation.) Journal of the Academy of Nutrition and Dietetics  , DOI: ( /j.jand ) Copyright © 2017 Academy of Nutrition and Dietetics Terms and Conditions

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