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Published byEugene Goodman Modified over 5 years ago
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Spine Intervention—An Update on Injectable Biomaterials
Nureddin Ashammakhi, MD, FRCSEd, PhD, Olivier Clerk-Lamalice, MD-MSc, FRCPC, Gamal Baroud, PhD, Mohammad Ali Darabi, PhD, Bassem Georgy, MD, Douglas Beall, MD, Derrick Wagoner, DO Canadian Association of Radiologists Journal Volume 70, Issue 1, Pages (February 2019) DOI: /j.carj Copyright © Terms and Conditions
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Figure 1 (A) Sagittal STIR weighted MR image shows a compression fracture of L1 (long arrow) and of the inferior endplate of T12 (short arrow). (B) Lateral fluoroscopic shot demonstrating adequate correction of the kyphotic angle after balloon inflation within the L1 vertebral body. (C) AP radiograph demonstrating adequate cement PMMA fill from pedicle to pedicle both for the L1 and T12 vertebral bodies. (D) CT with sagittal reformat demonstrating adequate antero-posterior PMMA fill. Canadian Association of Radiologists Journal , 37-43DOI: ( /j.carj ) Copyright © Terms and Conditions
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Figure 2 AP fluoroscopic shot performed after T12 and L1 PMMA kyphoplasty in a 72-year-old female. Adequate L1 fracture reduction with endplate-to-endplate and pedicle-to-pedicle PMMA filling. The long white arrow demonstrates a complete PMMA fill of a superior endplate fracture cleft. The VAS score decreased from a 9/10 prior to the intervention to a 1/10 after the procedure. Canadian Association of Radiologists Journal , 37-43DOI: ( /j.carj ) Copyright © Terms and Conditions
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Figure 3 Injectable bioactive glass bone cement with improved osteoinductivity and in vivo evaluation. PSC/CS, a phytic acid-derived bioactive glass/calcium sulfate. CSPC, combination of calcium sulfate cement and calcium phosphate cement. Column I, sagittal images, and column II and III, 3-D reconstructed images by micro-CT imaging of the area surrounding the cement implants after 12 weeks. The green and gray parts indicate newly formed bone, and residual cement, respectively. The bioactive glass cement led to improved bone regeneration in a critical-sized rabbit femoral condylar bone defects compared to those of PMMA and CP based cement. Reproduced from Zhu et al [38], licensed under a Creative Commons Attribution 4.0 International License. This figure is available in colour online at Canadian Association of Radiologists Journal , 37-43DOI: ( /j.carj ) Copyright © Terms and Conditions
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