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Excessive ovarian response is associated with increased expression of interleukin-2 in the periimplantation endometrium  Guneet Makkar, Ph.D., Ernest.

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Presentation on theme: "Excessive ovarian response is associated with increased expression of interleukin-2 in the periimplantation endometrium  Guneet Makkar, Ph.D., Ernest."— Presentation transcript:

1 Excessive ovarian response is associated with increased expression of interleukin-2 in the periimplantation endometrium  Guneet Makkar, Ph.D., Ernest Hung Yu Ng, M.D., William Shu Biu Yeung, Ph.D., Pak Chung Ho, M.D.  Fertility and Sterility  Volume 91, Issue 4, Pages (April 2009) DOI: /j.fertnstert Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Immunohistochemical expression of interleukin-2 (upper panels) and interferon-γ (lower panels) in human endometrial biopsy samples (magnification, ×630) from three groups of women and a negative control. The paraffin sections of peri-implantation endometrium were stained with monoclonal anti-human IL-2 antibody and with anti-human IFN-γ antibody. Peroxidase activity was visualized by application of diaminobenzidine tetrahydrochloride substrate and counterstained with hematoxylin. Glandular and stromal IL-2 expression were significantly higher in excessive responders compared with in moderate responders and in those from natural cycles. Interferon-γ expression in the glandular and stromal compartments was similar among the three groups. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

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