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Intermediate Results of Hybrid Versus Primary Norwood Operation

Published byἙκάβη Κακριδής Modified over 5 years ago

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Presentation on theme: "Intermediate Results of Hybrid Versus Primary Norwood Operation"— Presentation transcript:

1 Intermediate Results of Hybrid Versus Primary Norwood Operation
Daniel J. DiBardino, MD, Juliana Gomez-Arostegui, MD, MPH, Aaron Kemp, MS, Raveen Raviendran, MD, Sanjeet Hegde, MD, Eric J. Devaney, MD, John J. Lamberti, MD, Howaida El-Said, MD  The Annals of Thoracic Surgery  Volume 99, Issue 6, Pages (June 2015) DOI: /j.athoracsur Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Flow chart of stage I hospital discharge mortality for all 68 consecutive hypoplastic left heart syndrome variants. Stage I in this context refers to either Norwood or hybrid. (PGE = prostaglandin E1.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Kaplan-Meier actuarial survival curves with 95% confidence bounds for hybrid patients versus Norwood palliation indicate superior intermediate-term survival for the Norwood group (5-year 78% Norwood versus 56% for Hybrid, p = by log-rank analysis). (Group 1= Hybrid, group 2 = Norwood.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Kaplan-Meier actuarial survival curves with 95% confidence bounds for standard and high-risk hybrid and Norwood palliation indicate highly significant differences in intermediate-term survival (p = by log-rank analysis). (Group 1 = standard risk hybrid/ductal stent, group 2 = high-risk hybrid ductal stent, group 3= high-risk hybrid prostaglandin E1, group 4 = standard risk Norwood, group 5 = high-risk Norwood.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 Serial serum troponin measurements in the 8 patients having high-risk hybrid ductal stent. Note that after discharge, spikes in 4 patients (shown with arrows) led to a diagnosis of retrograde aortic arch obstruction and mandated early Norwood conversion. Late spikes peaked between 1 and 2.48. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

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