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Lipidomics as an emerging tool to predict endometrial receptivity

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Presentation on theme: "Lipidomics as an emerging tool to predict endometrial receptivity"— Presentation transcript:

1 Lipidomics as an emerging tool to predict endometrial receptivity
Felipe Vilella, Ph.D., Leslie B. Ramirez, B.S., Carlos Simón, M.D.  Fertility and Sterility  Volume 99, Issue 4, Pages (March 2013) DOI: /j.fertnstert Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Diagram showing the techniques available for lipidomic research. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

3 Figure 2 The lipidomics of endometrial fluid during the menstrual cycle. Endometrial fluid samples were obtained from healthy women throughout their natural menstrual cycles and were grouped into group I (days 0–8; n = 10), group II (days 9–14; n = 15), group III (days 15–18; n = 9), group IV (days 19–23; n = 9), and group V (days 24–30; n = 8). Samples were analyzed for changes in lipid content. Prostaglandin (PG) E2 and PGF2α levels were significantly increased in group IV (during the window of implantation) compared with lipid levels in all of the other groups throughout the menstrual cycle (Mann-Whitney U test: P<.01). Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions


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