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Pharmacokinetics of Murine p75-Fc Fusion Protein and MP6-XT22 Anti-Murine TNF-α mAb in Mice  Scott G. Filler, Norma V. Solis, Jane Guo, George Doellgast,

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Presentation on theme: "Pharmacokinetics of Murine p75-Fc Fusion Protein and MP6-XT22 Anti-Murine TNF-α mAb in Mice  Scott G. Filler, Norma V. Solis, Jane Guo, George Doellgast,"— Presentation transcript:

1 Pharmacokinetics of Murine p75-Fc Fusion Protein and MP6-XT22 Anti-Murine TNF-α mAb in Mice 
Scott G. Filler, Norma V. Solis, Jane Guo, George Doellgast, Ana Ruiz-Garcia, Wei-Jian Pan  Journal of Investigative Dermatology Symposium Proceedings  Volume 12, Issue 1, Pages (May 2007) DOI: /sj.jidsymp Copyright © 2007 The Society for Investigative Dermatology, Inc Terms and Conditions

2 Figure 1 Serum concentrations of (a) the MP6-XT22 rat anti-murine TNF-α mAb and (b) the murine p75-Fc protein in mice without infection and in mice with disseminated candidiasis. (a) Mean±SEM of three mice per time point. None of the infected mice survived beyond day 7, precluding comparisons at days 14 and 21. (b) Mean±SEM of 6–7 mice per time point (*P<0.05 using t-test: statistically significant difference between infected and uninfected mice). Journal of Investigative Dermatology Symposium Proceedings  , 52-56DOI: ( /sj.jidsymp ) Copyright © 2007 The Society for Investigative Dermatology, Inc Terms and Conditions


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