1. Hemostatic effects of fibrinogen concentrate compared with cryoprecipitate in children after cardiac surgery: A randomized pilot trial 
Filomena R.B.G. Galas, MD, PhD, Juliano P. de Almeida, MD, PhD, Júlia T. Fukushima, MSc, Jean Louis Vincent, MD, PhD, Eduardo A. Osawa, MD, PhD, Suely Zeferino, RN, Lígia Câmara, RN, Vanessa A. Guimarães, MD, Marcelo B. Jatene, MD, PhD, Ludhmila A. Hajjar, MD, PhD 
The Journal of Thoracic and Cardiovascular Surgery 
Volume 148, Issue 4, Pages (October 2014)
DOI: /j.jtcvs
Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

2. Figure 1
Protocol of treatment. CPB, Cardiopulmonary bypass; cT, central temperature; iCa, ionized calcium; ACT, Activated Clotting Time.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs )
Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

3. Figure 2 Flowchart of the study. ITT, Intention-to-treat.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs )
Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

4. Figure 3
Plasma levels of fibrinogen in fibrinogen concentrate and cryoprecipitate groups. There were no differences between groups at the fixed time points. *Plasma levels of fibrinogen are higher at T1, T2, T3, and T4 than T0 in both groups (P < .001). T1, One hour after study drug infusion; T2, 2 hours after study drug infusion; T3, 24 hours after study drug infusion; T4, 48 hours after study drug infusion; T0, before randomization.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs )
Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions