1. Grepafloxacin: pharmacokinetics and tissue penetration
Richard Wise 
Clinical Microbiology and Infection 
Volume 4, Pages S21-S24 (March 1998)
DOI: /j tb00685.x
Copyright © 1998 European Society of Clinical Infectious Diseases Terms and Conditions

2. Figure 1
Concentration-time curves of grepafloxacin in plasma (•) and inflammatory fluid (▴) in six healthy volunteers. Reproduced with kind permission from the American Society for Microbiology, from Child et al [2].
Clinical Microbiology and Infection 1998 4, S21-S24DOI: ( /j tb00685.x)
Copyright © 1998 European Society of Clinical Infectious Diseases Terms and Conditions

3. Figure 2
Accumulation of quinolones in polymorphonuclear leukocytes. Based on Taira et al [10].
Clinical Microbiology and Infection 1998 4, S21-S24DOI: ( /j tb00685.x)
Copyright © 1998 European Society of Clinical Infectious Diseases Terms and Conditions

4. Figure 3
Penetration of tissues in the respiratory tract by grepafloxacin, 400 mg/day, for 4 days. Reproduced with permission from Cook et al [11]. MIC value for Streptococcus pneumoniae taken from Pankuch et al [12].
Clinical Microbiology and Infection 1998 4, S21-S24DOI: ( /j tb00685.x)
Copyright © 1998 European Society of Clinical Infectious Diseases Terms and Conditions