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Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors for Non–Small-Cell Lung Cancer Patients with Leptomeningeal Carcinomatosis  Bin-Chi Liao,

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Presentation on theme: "Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors for Non–Small-Cell Lung Cancer Patients with Leptomeningeal Carcinomatosis  Bin-Chi Liao,"— Presentation transcript:

1 Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors for Non–Small-Cell Lung Cancer Patients with Leptomeningeal Carcinomatosis  Bin-Chi Liao, MD, Jih-Hsiang Lee, MD, Chia-Chi Lin, Ya-Fang Chen, MD, Chin-Hao Chang, PhD, Chao-Chi Ho, MD, PhD, Jin-Yuan Shih, MD, PhD, Chong-Jen Yu, MD, PhD, James Chih-Hsin Yang, MD, PhD  Journal of Thoracic Oncology  Volume 10, Issue 12, Pages (December 2015) DOI: /JTO Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Overall survival of all patients from diagnosis of leptomeningeal carcinomatosis to death. Journal of Thoracic Oncology  , DOI: ( /JTO ) Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Kaplan–Meier analysis showing overall survival of all patients who (A) received (red) or did not receive (blue) epidermal growth factor receptor tyrosine kinase inhibitor therapy after diagnosis of leptomeningeal carcinomatosis (LC); (B) received (red) or did not receive (blue) cytotoxic chemotherapy after diagnosis of LC; (C) received (red) or did not receive (blue) whole-brain radiation therapy after diagnosis of LC; (D) received (red) or did not receive (blue) intrathecal chemotherapy after diagnosis of LC. Journal of Thoracic Oncology  , DOI: ( /JTO ) Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

4 FIGURE 3 Kaplan–Meier analysis showing overall survival of patients with epidermal growth factor receptor (EGFR) mutations who (A) received (red) or did not receive (blue) EGFR tyrosine kinase inhibitor therapy after diagnosis of leptomeningeal carcinomatosis; (B) received (red) or did not receive (blue) cytotoxic chemotherapy after diagnosis of LC; (C) received (red) or did not receive (blue) whole-brain radiation therapy after diagnosis of leptomeningeal carcinomatosis. Journal of Thoracic Oncology  , DOI: ( /JTO ) Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

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