1. Dynamic loading enhances integrative meniscal repair in the presence of interleukin-1 
A.L. McNulty, B.T. Estes, R.E. Wilusz, J.B. Weinberg, F. Guilak 
Osteoarthritis and Cartilage 
Volume 18, Issue 6, Pages (June 2010)
DOI: /j.joca
Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

2. Fig. 1
MMP activity in the media of meniscal repair model explants that were exposed to no strain, strain, no strain+IL-1, or strain+IL-1. The strains tested were 1% (top panel), 10% (middle panel), and 26% (bottom panel). The MMP activity is expressed as fluorescence units (FU)/mg wet weight+standard error. *: P<0.05 compared to all other treatments.
Osteoarthritis and Cartilage  , DOI: ( /j.joca )
Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

3. Fig. 2
ADAMTS-4 activity in the media of meniscal repair model explants that were exposed to no strain, strain, no strain+IL-1, or strain+IL-1. The strains tested were 1% (top panel), 10% (middle panel), and 26% (bottom panel). The aggrecanase activity is expressed as fluorescence units (FU)/mg wet weight+standard error.
Osteoarthritis and Cartilage  , DOI: ( /j.joca )
Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

4. Fig. 3
S-GAG release into the media of meniscal repair model explants that were exposed to no strain, strain, no strain+IL-1, or strain+IL-1. The strains tested were 1% (top panel), 10% (middle panel), and 26% (bottom panel). The S-GAG release is expressed as μg S-GAG/mg wet weight+standard error. *: P≤0.005 compared to all other treatments. +: P<0.01 compared to no strain and strain.
Osteoarthritis and Cartilage  , DOI: ( /j.joca )
Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

5. Fig. 4
NO release into the media of meniscal repair model explants that were exposed to no strain, strain, no strain+IL-1, or strain+IL-1. The strains tested were 1% (top panel), 10% (middle panel), and 26% (bottom panel). The NO release is expressed as μmol/g wet weight+standard error. *: P<0.005 compared to all other treatments. +: P<0.05 compared to no strain.
Osteoarthritis and Cartilage  , DOI: ( /j.joca )
Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

6. Fig. 5
Integrative shear strength of repair for meniscal repair model explants that were exposed to no strain, strain, no strain+IL-1, or strain+IL-1. The strains tested were 1% (top panel), 10% (middle panel), and 26% (bottom panel). The shear strength of repair is expressed as kPa+standard error. *: P<0.05 compared to all other treatments. #: P<0.005 compared to no strain and no strain+IL-1. +: P<0.01 compared to 26% strain+IL-1.
Osteoarthritis and Cartilage  , DOI: ( /j.joca )
Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

7. Fig. 6
Histological images of paraffin embedded meniscal repair model explants stained with Hematoxylin to identify the cell nuclei (black), fast green (green) to identify the collagen fibers, and Safranin O (red) to stain proteoglycans. Samples were incubated with no IL-1 or 100pg/mL IL-1 and subjected to 0%, 1%, 10%, or 26% strain. Scale bar is equal to 100μm.
Osteoarthritis and Cartilage  , DOI: ( /j.joca )
Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions