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The extent of barrett's esophagus depends on the status of the lower esophageal sphincter and the degree of esophageal acid exposure  Stefan Öberg, MD*,

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Presentation on theme: "The extent of barrett's esophagus depends on the status of the lower esophageal sphincter and the degree of esophageal acid exposure  Stefan Öberg, MD*,"— Presentation transcript:

1 The extent of barrett's esophagus depends on the status of the lower esophageal sphincter and the degree of esophageal acid exposure  Stefan Öberg, MD*, Tom R. DeMeester, MD, Jeffrey H. Peters, MD, Jeffrey A. Hagen, MD, John J. Nigro, MD, Steven R. DeMeester, MD, Jörg Theisen, MD, Guilherme M.R. Campos, MD, Peter F. Crookes, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 117, Issue 3, Pages (March 1999) DOI: /S (99) Copyright © 1999 Mosby, Inc. Terms and Conditions

2 Fig. 1 The prevalence of intestinal metaplasia occurring within cardiac-type mucosa of varying extents: limited to the gastroesophageal (GE) junction, involving short (<3 cm) and long (≥3 cm) segments of the esophageal body. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (99) ) Copyright © 1999 Mosby, Inc. Terms and Conditions

3 Fig. 2 The relationship between the extent of cardiac-type mucosa with intestinal metaplasia (IM) and resting pressure of the lower esophageal sphincter (LESP) on standard esophageal manometry. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (99) ) Copyright © 1999 Mosby, Inc. Terms and Conditions

4 Fig. 3 The relationship between the extent of cardiac-type mucosa with intestinal metaplasia (IM) and lower esophageal sphincter (LES) abdominal length on standard esophageal manometry. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (99) ) Copyright © 1999 Mosby, Inc. Terms and Conditions

5 Fig. 4 The relationship between the extent of cardiac-type mucosa with intestinal metaplasia (IM) and degree of lower esophageal sphincter (LES) competency. Values of each subject are plotted; the horizontal line denotes the mean of each group. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (99) ) Copyright © 1999 Mosby, Inc. Terms and Conditions

6 Fig. 5 The relationship between the extent of cardiac-type mucosa with intestinal metaplasia (IM) and the percentage of time spent below pH 4.0 on 24-hour esophageal pH monitoring. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (99) ) Copyright © 1999 Mosby, Inc. Terms and Conditions

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