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Abandoning FEV1/FVC <0.70 to Detect Airway Obstruction

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Presentation on theme: "Abandoning FEV1/FVC <0.70 to Detect Airway Obstruction"— Presentation transcript:

1 Abandoning FEV1/FVC <0.70 to Detect Airway Obstruction
Bas Robberts, MD, Tjard Schermer, PhD  CHEST  Volume 139, Issue 5, Pages (May 2011) DOI: /chest Copyright © 2011 The American College of Chest Physicians Terms and Conditions

2 Figure 1 Association between FEV1/FVC and age in male symptomatic current and ex-smokers aged ≥ 50 years referred for spirometric testing by their primary care physician (n = 3,473). The horizontal red line indicates the fixed 0.70 FEV1/FVC cutoff point that is currently recommended by all major clinical COPD guidelines; the black diagonal line indicates the lower limit of normal for healthy nonsmoking men. Black circles = true negatives; green circles = true positives (unique subjects considered to have airflow obstruction according to both definitions); red circles = false positives (subjects in whom discordant conclusions regarding the presence of airflow obstruction are drawn, n = 558, 16% of all subjects). (Adapted with permission from Schermer et al.4) CHEST  , DOI: ( /chest ) Copyright © 2011 The American College of Chest Physicians Terms and Conditions


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