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Modified antigenic reactivity of anti-phospholipase A2 IgG antibodies in patients allergic to bee venom: Conversion with immunotherapy and relation to.

Published byÁngela Marín Modified over 5 years ago

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Presentation on theme: "Modified antigenic reactivity of anti-phospholipase A2 IgG antibodies in patients allergic to bee venom: Conversion with immunotherapy and relation to."— Presentation transcript:

1 Modified antigenic reactivity of anti-phospholipase A2 IgG antibodies in patients allergic to bee venom: Conversion with immunotherapy and relation to subclass expression  Alain Michils, MD, PhDa, Michel Mairesse, MDb, Claire Ledent, MDb, Béatrice Gossart, BSc, Sandra Baldassarre, MDa, Jean Duchateau, MD, PhDc  Journal of Allergy and Clinical Immunology  Volume 102, Issue 1, Pages (July 1998) DOI: /S (98) Copyright © 1998 Mosby, Inc. Terms and Conditions

2 Fig. 1 Frequency histograms of specific IgG titers after natural logarithmic transformation for allergic (preimmunotherapy), VIT, and healthy control populations. Journal of Allergy and Clinical Immunology  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

3 Fig. 2 Distribution of percentage inhibitions of allergic pooled IgG binding to PLA2 by individual sera from allergic (preimmunotherapy), VIT, and healthy control groups. Journal of Allergy and Clinical Immunology  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

4 Fig. 3 Distribution of percentage inhibitions of VIT-pooled IgG binding to PLA2 by individual sera from allergic (preimmunotherapy), VIT, and healthy control groups. Journal of Allergy and Clinical Immunology  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

5 Fig. 4 Evolution of mean inhibition capacity of sera from allergic patients during VIT (binding inhibition of allergic [preimmunotherapy] and VIT-pooled IgG fraction). Journal of Allergy and Clinical Immunology  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

6 Fig. 5 Inhibition of binding of allergic pooled IgG1 (A) and IgG4 (B) by pooled sera from allergic patients, healthy individuals, and patients receiving VIT for 15 days and 2 years. Journal of Allergy and Clinical Immunology  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

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