1. Volume 13, Issue 1, Pages 39-49 (February 2006)
Variability of bacterial translocation in the absence of intestinal mucosal damage following injury and the influence of interleukin-6 
Hirobumi Gunji, Sylvia Scarth, Gordon L. Carlson, Geoffrey Warhurst, Rodney A. Little, Stephen J. Hopkins 
Pathophysiology 
Volume 13, Issue 1, Pages (February 2006)
DOI: /j.pathophys
Copyright © 2005 Elsevier Ireland Ltd Terms and Conditions

2. Fig. 1
Bacterial translocation and intestinal mucosal morphology following haemorrhage at 35mmHg. C57Bl/6 mice were subjected to 35mmHg (H-35; n=6) or 20mmHg (H-20; n=9) haemorrhage for 60min and allowed to recover for 16h. Bacterial counts from liver spleen and MLN, and intestinal mucosal morphology, were assessed and compared to samples from control animals (n=9). Horizontal bars represent median values. Boxes represent the 25th and 75th percentile and whiskers show the range for morphological data. The total bacterial counts for all organs were not significantly different between haemorrhaged and control animals (p=0.67 for H-35 and p=0.08 for H-20 mice).
Pathophysiology  , 39-49DOI: ( /j.pathophys )
Copyright © 2005 Elsevier Ireland Ltd Terms and Conditions

3. Fig. 2
Bacterial translocation following haemorrhage at 35mmHg in Balb/c mice. Balb/c mice were subjected to 35mmHg haemorrhage (n=8) for 60min and allowed to recover for 16h. Bacterial counts from liver, spleen and MLN were assessed and compared to samples from controls (n=7). Horizontal bars represent median values. The total bacterial counts for all organs were not significantly different between haemorrhaged and control animals (p=0.08).
Pathophysiology  , 39-49DOI: ( /j.pathophys )
Copyright © 2005 Elsevier Ireland Ltd Terms and Conditions

4. Fig. 3
Bacterial translocation and intestinal mucosal morphology in IL-6+/+ mice following haemorrhage. Following withdrawal of food for 18h, IL-6+/+ mice were subjected to 35mmHg haemorrhage (n=9) for 60min. Bacterial counts from liver, spleen and MLN (n=6), and intestinal mucosal morphology, were assessed and compared to samples from controls. Data is represented as in Fig. 1 (median values). The total bacterial counts for all organs were not significantly different between haemorrhaged and control animals (p=0.26).
Pathophysiology  , 39-49DOI: ( /j.pathophys )
Copyright © 2005 Elsevier Ireland Ltd Terms and Conditions

5. Fig. 4
Bacterial translocation and intestinal mucosal morphology in IL-6−/− mice following withdrawal of food. Following withdrawal of food for 18h, IL-6−/− mice were subjected to 25mmHg haemorrhage (n=3 survivors of 10 operative procedures) for 60min. Bacterial counts from liver spleen and MLN and intestinal mucosal morphology, were assessed and compared to samples from controls (n=6). Data is represented as in Fig. 1. The total bacterial counts for all organs were not significantly different between haemorrhaged and control animals (p>0.6).
Pathophysiology  , 39-49DOI: ( /j.pathophys )
Copyright © 2005 Elsevier Ireland Ltd Terms and Conditions

6. Fig. 5
Bacterial translocation and intestinal mucosal morphology in IL-6+/+ mice (n=6) subjected to 25mmHg haemorrhage for 90min. Following withdrawal of food for 18h, mice were subjected to 25mmHg haemorrhage (n=9 survivors of 11 operative procedures) for 90min. Data are represented as in Fig. 1. The total bacterial counts for all organs were not significantly different between animals subjected to hind limb ischaemia and control animals (p>0.1).
Pathophysiology  , 39-49DOI: ( /j.pathophys )
Copyright © 2005 Elsevier Ireland Ltd Terms and Conditions

7. Fig. 6
Bacterial counts and intestinal mucosal morphology of IL-6+/+ and IL-6−/− mice subjected to hind limb ischaemia. IL-6+/+ (n=6) and IL-6−/− (n=7) mice were subjected to hind limb ischaemia for 60min. Bacterial counts were assessed in tissues of all mice subjected to hind limb ischaemia, as well as in 9 control IL-6+/+ and 10 control IL-6−/− mice. Measurements of mucosal morphology were made in all IL-6+/+ and IL-6−/− mice subject to ischaemia and in three control IL-6+/+ and four control IL-6−/− mice. Data are represented as in Fig. 1. The total bacterial counts for all organs were not significantly different between animals subjected to hind limb ischaemia and control animals (p=0.09 for IL-6+/+ and p=0.34 for IL-6−/− mice).
Pathophysiology  , 39-49DOI: ( /j.pathophys )
Copyright © 2005 Elsevier Ireland Ltd Terms and Conditions