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Use of a bovine jugular vein graft with natural valve for right ventricular outflow tract reconstruction: A one-year animal study  Yukio Ichikawa, MD,

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Presentation on theme: "Use of a bovine jugular vein graft with natural valve for right ventricular outflow tract reconstruction: A one-year animal study  Yukio Ichikawa, MD,"— Presentation transcript:

1 Use of a bovine jugular vein graft with natural valve for right ventricular outflow tract reconstruction: A one-year animal study  Yukio Ichikawa, MD, PhD, Yasuharu Noishiki, MD, PhD, Takayuki Kosuge, MD, PhD, Kenji Yamamoto, MD, PhD, Jiro Kondo, MD, PhD, Akihiko Matsumoto, MD, PhD  The Journal of Thoracic and Cardiovascular Surgery  Volume 114, Issue 2, Pages (August 1997) DOI: /S (97) Copyright © 1997 Mosby, Inc. Terms and Conditions

2 Fig. 1 Microscopic observation of the luminal surface of the prepared graft. The graft was composed of collagen fibers and elastic laminae. Arrowheads indicate leaflet. (Victoria blue staining; original magnification ×100.) The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (97) ) Copyright © 1997 Mosby, Inc. Terms and Conditions

3 Fig. 2 The natural trileaflet valve of bovine jugular vein graft. Left, Systole: The leaflets opened softly. Center, Midsystole. Right, Diastole: The leaflets closed completely. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (97) ) Copyright © 1997 Mosby, Inc. Terms and Conditions

4 Fig. 3 The bovine jugular vein graft. The outer surface has rough collagen velour. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (97) ) Copyright © 1997 Mosby, Inc. Terms and Conditions

5 Fig. 4 The right ventricular–pulmonary arterial (RV-PA) bypass with the new graft. The outer wall of the valve is slightly ballooned. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (97) ) Copyright © 1997 Mosby, Inc. Terms and Conditions

6 Fig. 5 The pressure gradient across the conduit valve at 385 days after the operation. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (97) ) Copyright © 1997 Mosby, Inc. Terms and Conditions

7 Fig. 6 Right ventriculogram 182 days after the operation. The conduit was patent, unkinked, and undilated. Arrowheads indicate the conduit. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (97) ) Copyright © 1997 Mosby, Inc. Terms and Conditions

8 Fig. 7 Echocardiograms of the graft 385 days after the operation. RV, Right ventricle; PA, pulmonary artery. Valvular swaying is maintained satisfactorily. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (97) ) Copyright © 1997 Mosby, Inc. Terms and Conditions

9 Fig. 8 The inner surface of the explanted graft 196 days after the operation. No intimal hyperplasia and no thrombus is apparent on the luminal surface of the graft except for a small thrombus on the valve. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (97) ) Copyright © 1997 Mosby, Inc. Terms and Conditions

10 Fig. 9 Microscopic observation of the luminal surface of the graft 385 days after the operation. (Van Gieson elastin stain; original magnification ×100.) The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (97) ) Copyright © 1997 Mosby, Inc. Terms and Conditions

11 Fig. 10 Microscopic observation of the luminal surface of the graft 385 days after the operation. (von Kossa staining; original magnification ×100.) The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (97) ) Copyright © 1997 Mosby, Inc. Terms and Conditions

12 Fig. 11 Microscopic observation of the luminal surface of the graft 182 days after the operation. The graft shows endothelium-like cells. (Hematoxylin and eosin staining; original magnification ×100.) The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (97) ) Copyright © 1997 Mosby, Inc. Terms and Conditions

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