1. Volume 16, Issue 5, Pages 490-498 (May 2009)
Dissecting Structural and Functional Diversity of the Lantibiotic Mersacidin 
Antony N. Appleyard, Shaila Choi, Daniel M. Read, Ann Lightfoot, Steven Boakes, Anja Hoffmann, Ian Chopra, Gabriele Bierbaum, Brian A.M. Rudd, Michael J. Dawson, Jesus Cortes 
Chemistry & Biology 
Volume 16, Issue 5, Pages (May 2009)
DOI: /j.chembiol
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2. Figure 1 The Structure of Mersacidin and Its Gene Cluster
(A) Primary structure of mersacidin indicating the sequence and thioether bridge pattern.
(B) Organization of the mersacidin biosynthetic gene cluster.
(C) Engineered system for generating mersacidin mutants. Da, dehydroalanine; Ab, 2-aminobutyrate.
Chemistry & Biology  , DOI: ( /j.chembiol )
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3. Figure 2 Mersacidin Substitution Library
Under the linear representation of mersacidin, the circles indicate the variants that were detected by LC-MS. Gray circles indicate variants produced at high yield (>10%, versus mersacidin production), and white circles indicate variants produced at trace levels. Da, dehydroalanine; Db, dehydrobutyrine; Ab, 2-aminobutyrate.
Chemistry & Biology  , DOI: ( /j.chembiol )
Copyright © 2009 Elsevier Ltd Terms and Conditions

4. Figure 3 Mersacidin Insertion Library
Under the linear representation of mersacidin, the arrows indicate the positions where residues were inserted, and the circles indicate the insertion variants that were detected by LC-MS. Gray circles indicate variants produced at high yield (>10%, versus mersacidin production), and white circles indicate variants produced at trace levels. Da, dehydroalanine; Db, dehydrobutyrine; Ab, 2-aminobutyrate.
Chemistry & Biology  , DOI: ( /j.chembiol )
Copyright © 2009 Elsevier Ltd Terms and Conditions