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Early adaptation of human lower extremity vein grafts: wall stiffness changes accompany geometric remodeling  Jeffrey G. Jacot, BS, Ibrahim Abdullah,

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Presentation on theme: "Early adaptation of human lower extremity vein grafts: wall stiffness changes accompany geometric remodeling  Jeffrey G. Jacot, BS, Ibrahim Abdullah,"— Presentation transcript:

1 Early adaptation of human lower extremity vein grafts: wall stiffness changes accompany geometric remodeling  Jeffrey G. Jacot, BS, Ibrahim Abdullah, BS, Michael Belkin, MD, Marie Gerhard-Herman, MD, Peter Gaccione, MA, Joseph F. Polak, MD, MPH, Magruder C. Donaldson, MD, Anthony D. Whittemore, MD, Michael S. Conte, MD  Journal of Vascular Surgery  Volume 39, Issue 3, Pages (March 2004) DOI: /j.jvs

2 Fig 1 A, M-mode ultrasound scan image of graft cross-section used for dimensional measurements. B, Duplex Doppler ultrasound scan image of graft used for PWV measurement. Journal of Vascular Surgery  , DOI: ( /j.jvs )

3 Fig 1 A, M-mode ultrasound scan image of graft cross-section used for dimensional measurements. B, Duplex Doppler ultrasound scan image of graft used for PWV measurement. Journal of Vascular Surgery  , DOI: ( /j.jvs )

4 Fig 2 The overall population showed an increase in both pulse wave velocity (P = .08) and wall stiffness (P = .02) over the first 6 months after bypass graft. Graphed values are presented as the mean ± SEM. Journal of Vascular Surgery  , DOI: ( /j.jvs )

5 Fig 3 Elastic modulus (E) in the overall cohort of vein grafts. The maximal observed change was between 1 and 3 months after surgery (P = NS). Graphed values are presented as the mean ± SEM. Journal of Vascular Surgery  , DOI: ( /j.jvs )

6 Fig 4 The percentage of change in lumen diameter in the overall cohort over the first 3 months after implantation shows a negative correlation with the initial lumen diameter (n = 26; R2 = .37; P < .001). Large grafts (diameter > cm) increased their diameters by 8% ± 4%, whereas small grafts (diameters < cm) increased their diameters by 26% ± 13%. These populations were significantly different (P < .05). Journal of Vascular Surgery  , DOI: ( /j.jvs )


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