1. Example of nocturnal oxygen desaturation (NOD) and its physiological consequences.
Example of nocturnal oxygen desaturation (NOD) and its physiological consequences. Sleep stage (rapid eye movement [REM] in bold) and transcutaneous oxygen measurements during sleep in a subject with COPD. Hypoxemia worsens during sleep, most substantially during periods of REM sleep. During periods of NOD there are increases in pulmonary and systemic blood pressure. Administration of supplemental oxygen improves NOD and prevents increases in pressure. (From Reference 24, with permission.)‏
Robert L Owens Respir Care 2013;58:32-47
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