1. DNA and Mutation Chapter 25
**don’t forget about rDNA which didn’t make the game 
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2. DNA Structure
Mutation
Replication
Transcription
Translation
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3. DNA Structure 100
These 3 scientists are known for discovering the structure of DNA.
A: Who is Watson, Crick & Franklin?
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4. DNA Structure 200
Name the 2 kinds of molecules that make up the backbone of the DNA molecule.
A: What are deoxyribose sugars and phosphates?
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5. DNA Structure 300
Name the nitrogen bases used to make the DNA code & their complementary base pairing
A: What are Adenine with Thymine & Guanine with Cytosine?
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6. DNA Structure 400
Names of the two categories of bases & the bases that belong to each A
A: What are purines (A & G) and pyrimidines (C & T) ? G
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7. DNA Structure 500 Draw & label a portion of DNA including H-bonds
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8. Mutation 100 Causes of mutations
A: What are radiation, chemicals, spontaneous via DNA replication ?
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9. Mutation 200 Two potential locations & difference between them.
A: What is germline in the egg/sperm which is inheritable to offspring & somatic in all other cells which can not be passed along to offspring?
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10. Mutation 300 Reasons cancer cells are unique.
A: What is no differentiation, abnormal nuclei, form tumours, undergo angiogenesis & metastasize?
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11. Mutation 400 Types of frameshift mutations
A: What is insertion & deletion ?
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12. Mutation 500 4 types of chromosomal mutations.
A: What is deletion, duplication, inversion, translocation?
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13. Purpose of replication.
A: What is growth & repair?
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14. Main enzyme that joins nucleotides to make a DNA molecule
Replication 200
Main enzyme that joins nucleotides
to make a DNA molecule
A: What is DNA polymerase?
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15. Give the complementary DNA code for: A T G G C T
Replication 300
Give the complementary DNA code for:
A T G G C T
A: What is: T A C C G A ?
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16. The first enzyme that “unwinds & unzips” DNA breaking the H-bonds
Replication 400
The first enzyme that “unwinds & unzips” DNA breaking the H-bonds
A: What is DNA helicase?
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17. Replication 500
Enzyme responsible for repair any breaks in the backbone which occurs on the lagging strand
A: What is DNA ligase?
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18. Transcription 100 Name the 3 kinds of RNA produced by transcription
A: What are messenger-RNA, transfer-RNA, and ribosomal-RNA?
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19. Transcription 200 Transcribe the following DNA: ATT CTG TGA
A: What is UAA GAC ACU?
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20. Transcription 300
Enzyme that unwinds the DNA for transcription to occur
A: What is RNA polymerase?
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21. Transcription 400
Sequences of DNA that are cut out of the corresponding RNA molecule while it is still in the nucleus
A: What are introns ?
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22. Transcription 500
The DNA strand that serves as the “template” for transcription.
A: What is: the sense strand?
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23. Subunits that are joined together to make proteins
Translation 100
Subunits that are joined together to make proteins
A: What are amino acids?
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24. Translation 200
Place in cell where proteins are assembled & what this organelle is made up off.
A: What is on the ribosomes which have 2 subunits made up of rRNA & proteins?
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25. Describe the structure of tRNA.
Translation 300
Describe the structure of tRNA.
A: What is anticodon on one end & carrying a specific amino acid on the other?
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26. List the 3 steps to translation.
A: What is initiation, elongation, & termination?
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27. Translation 500 A: What is peptide bonds?
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Translation 500
What type of bonds join the amino acids?
A: What is peptide bonds?
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