Presentation is loading. Please wait.

Presentation is loading. Please wait.

A neonatal swine model for peanut allergy

Published by创 邬 Modified over 5 years ago

Similar presentations

Presentation on theme: "A neonatal swine model for peanut allergy"— Presentation transcript:

1 A neonatal swine model for peanut allergy
Ricki M. Helm, PhDa, Glenn T. Furuta, MDb, J.Steve Stanley, PhDa, Jianhui Ye, PhDa, Gael Cockrell, BSa, Cathie Connaughton, BSa, Pippa Simpson, PhDc, Gary A. Bannon, PhDa,d, A.Wesley Burks, MDa  Journal of Allergy and Clinical Immunology  Volume 109, Issue 1, Pages (January 2002) DOI: /mai Copyright © 2002 Mosby, Inc. Terms and Conditions

2 Fig. 1 Flow diagram shows the experimental regime.
Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2002 Mosby, Inc. Terms and Conditions

3 Fig. 2 Representative photographs of skin test results. Upper panel: Skin test results 1 week after a positive oral challenge with peanut meal. Lower panel: Skin test results from a nonsensitized piglet. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2002 Mosby, Inc. Terms and Conditions

4 Fig. 3 Intradermal skin challenge in peanut-sensitized and control swine at day 45. The mean for 7 peanut-sensitized animals (○) and the mean for 2 control animals (*) are represented. Representative P values are shown at the top of the figure. Identical values appear only once each. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2002 Mosby, Inc. Terms and Conditions

5 Fig. 4 Peanut-specific IgG levels in peanut-sensitized and control swine. Results are expressed as the means for 7 animals (○) in the peanut-sensitized group and 2 control animals (*). Represent-ative P values are shown at the top of the figure. Identical values appear only once each. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2002 Mosby, Inc. Terms and Conditions

6 Fig. 5 Histologic assessments of the small intestine in peanut-sensitized and nonsensitized control swine. A, Peanut-sensitized piglet after an oral challenge with peanut. B, Peanut-sensitized piglet that did not receive an oral challenge with peanut. Vascular congestion and edema of the mucosa and submucosa are evident in the sensitized swine sections (10×). Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2002 Mosby, Inc. Terms and Conditions

Download ppt "A neonatal swine model for peanut allergy"

Similar presentations

Superior biologic activity of the recombinant bee venom allergen hyaluronidase expressed in baculovirus-infected insect cells as compared with Escherichia.

Superior biologic activity of the recombinant bee venom allergen hyaluronidase expressed in baculovirus-infected insect cells as compared with Escherichia.
Efficacy and safety overview of a new inhaled corticosteroid, QVAR (hydrofluoroalkane- beclomethasone extrafine inhalation aerosol), in asthma Jennifer.

Efficacy and safety overview of a new inhaled corticosteroid, QVAR (hydrofluoroalkane- beclomethasone extrafine inhalation aerosol), in asthma Jennifer.
Reducing relative humidity to control the house dust mite Dermatophagoides farinae Larry G. Arlian, PhD, Jacqueline S. Neal, BS, DiAnn L. Vyszenski-Moher,

Reducing relative humidity to control the house dust mite Dermatophagoides farinae Larry G. Arlian, PhD, Jacqueline S. Neal, BS, DiAnn L. Vyszenski-Moher,
Anaphylaxis induced by horsefly bites: Identification of a 69 kd IgE-binding salivary gland protein from Chrysops spp. (Diptera Tabanidae) by western.

Anaphylaxis induced by horsefly bites: Identification of a 69 kd IgE-binding salivary gland protein from Chrysops spp. (Diptera Tabanidae) by western.
W.Travis Cain, MDa, Greg Cable, PhDb, John J. Oppenheimer, MDc 

W.Travis Cain, MDa, Greg Cable, PhDb, John J. Oppenheimer, MDc 
Double-blind placebo-controlled study of the efficacy of oral terfenadine in the treatment of chronic fatigue syndrome  Paul Steinberg, MDa, Bruce E.

Double-blind placebo-controlled study of the efficacy of oral terfenadine in the treatment of chronic fatigue syndrome  Paul Steinberg, MDa, Bruce E.
Kiwi fruit allergy: A new birch pollen–associated food allergy

Kiwi fruit allergy: A new birch pollen–associated food allergy
Different expression of cytokine and membrane molecules by circulating lymphocytes on acute mental stress in patients with atopic dermatitis in comparison.

Different expression of cytokine and membrane molecules by circulating lymphocytes on acute mental stress in patients with atopic dermatitis in comparison.
A clinical analysis of gelatin allergy and determination of its causal relationship to the previous administration of gelatin-containing acellular pertussis.

A clinical analysis of gelatin allergy and determination of its causal relationship to the previous administration of gelatin-containing acellular pertussis.
Sequence variation in the promoter region of the cholinergic receptor muscarinic 3 gene and asthma and atopy  Joseph Donfack, PhDa, Paul Kogut, BSb, Sean.

Sequence variation in the promoter region of the cholinergic receptor muscarinic 3 gene and asthma and atopy  Joseph Donfack, PhDa, Paul Kogut, BSb, Sean.
Isolation and characterization of a clone encoding a major allergen (Bla g Bd90K) involved in IgE-mediated cockroach hypersensitivity  Ricki Helm, PhDa,

Isolation and characterization of a clone encoding a major allergen (Bla g Bd90K) involved in IgE-mediated cockroach hypersensitivity  Ricki Helm, PhDa,
The editors’ choice Journal of Allergy and Clinical Immunology

The editors’ choice Journal of Allergy and Clinical Immunology
Eosinophil cationic protein and histamine after intestinal challenge in patients with cow's milk intolerance  Ulf Bengtsson, MD, PhDa, Tina W. Knutson,

Eosinophil cationic protein and histamine after intestinal challenge in patients with cow's milk intolerance  Ulf Bengtsson, MD, PhDa, Tina W. Knutson,
Wheat α-amylase inhibitor: A second route of allergic sensitization

Wheat α-amylase inhibitor: A second route of allergic sensitization
Kiwi fruit allergy: A new birch pollen–associated food allergy

Kiwi fruit allergy: A new birch pollen–associated food allergy
Asthma and increased bronchial responsiveness in elite athletes: Atopy and sport event as risk factors  Ilkka J. Helenius, MDa, Heikki O. Tikkanen, MDb,

Asthma and increased bronchial responsiveness in elite athletes: Atopy and sport event as risk factors  Ilkka J. Helenius, MDa, Heikki O. Tikkanen, MDb,
Comparison of once-daily ebastine 20 mg, ebastine 10 mg, loratadine 10 mg, and placebo in the treatment of seasonal allergic rhinitis  Paul H. Ratner,

Comparison of once-daily ebastine 20 mg, ebastine 10 mg, loratadine 10 mg, and placebo in the treatment of seasonal allergic rhinitis  Paul H. Ratner,
Practice Notes from the AAAI

Practice Notes from the AAAI
Badrul A. Chowdhury, MD, PhD 

Badrul A. Chowdhury, MD, PhD 
Hydroxychloroquine improves airflow and lowers circulating IgE levels in subjects with moderate symptomatic asthma  B.Lauren Charous, MD, Elkan F. Halpern,

Hydroxychloroquine improves airflow and lowers circulating IgE levels in subjects with moderate symptomatic asthma  B.Lauren Charous, MD, Elkan F. Halpern,

Similar presentations

Ads by Google