1. Amrinone can accelerate the cooling rate of core temperature during deliberate mild hypothermia for neurosurgical procedures 
S. Inoue, M. Kawaguchi, T. Sakamoto, T. Iwata, Y. Kawaraguchi, H. Furuya, T. Sakaki 
British Journal of Anaesthesia 
Volume 86, Issue 5, Pages (May 2001)
DOI: /bja/
Copyright © 2001 British Journal of Anaesthesia Terms and Conditions

2. Fig 1
Intraoperative changes in tympanic membrane temperature and skin surface temperature gradient (forearm minus fingertip). Tympanic membrane temperature 30–90 min after cooling was significantly lower in the amrinone (AMR) group than in the control group. The temperature gradient 30 min after the cooling was significantly lower in the amrinone group than in the control group. The amrinone group received a loading dose of amrinone 1.0 mg–1 kg–1 then an infusion of amrinone 5 µg kg–1 min–1; the control group did not receive amrinone. The data are expressed as mean (sem). Comparisons between the two groups were performed by two-way analysis of variance for repeated measures followed by Fisher’s protected least significant difference test. *P<0.05 versus control group; **P<0.01 versus control group.
British Journal of Anaesthesia  , DOI: ( /bja/ )
Copyright © 2001 British Journal of Anaesthesia Terms and Conditions

3. Fig 2
Intraoperative changes in heart rate and mean arterial blood pressure. There were no significant differences between the two groups in heart rate at each time interval during the operation. Mean arterial blood pressure at the beginning of the rewarming was significantly lower in the amrinone (AMR) group than in the control group. There were no significant differences between the two groups in heart rate at each time interval during the operation. The amrinone group received a loading dose of amrinone 1.0 mg–1 kg–1 then an infusion of amrinone 5 µg kg–1 min–1; the control group did not receive amrinone. The data are expressed as mean (sem). Comparisons between the two groups were performed by two-way analysis of variance for repeated measures followed by Fisher’s protected least significant difference test. *P<0.05 versus control group; **P<0.01 versus control group.
British Journal of Anaesthesia  , DOI: ( /bja/ )
Copyright © 2001 British Journal of Anaesthesia Terms and Conditions