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Runs of Homozygosity: Association with Coronary Artery Disease and Gene Expression in Monocytes and Macrophages Paraskevi Christofidou, Christopher P. Nelson, Majid Nikpay, Liming Qu, Mingyao Li, Christina Loley, Radoslaw Debiec, Peter S. Braund, Matthew Denniff, Fadi J. Charchar, Ares Rocanin Arjo, David-Alexandre Trégouët, Alison H. Goodall, Francois Cambien, Willem H. Ouwehand, Robert Roberts, Heribert Schunkert, Christian Hengstenberg, Muredach P. Reilly, Jeanette Erdmann, Ruth McPherson, Inke R. König, John R. Thompson, Nilesh J. Samani, Maciej Tomaszewski The American Journal of Human Genetics Volume 97, Issue 2, Pages (August 2015) DOI: /j.ajhg Copyright © 2015 The American Society of Human Genetics Terms and Conditions
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Figure 1 Overview of the Project Strategy
The American Journal of Human Genetics , DOI: ( /j.ajhg ) Copyright © 2015 The American Society of Human Genetics Terms and Conditions
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Figure 2 Analysis of Association between the Presence of Consensus ROHs and Gene Expression in the Cardiogenics Study: Genome-wide Signal-Intensity Plot (A) Human monocytes. (B) Human macrophages. The y axis shows the logarithmic level of statistical significance (p value) for association of each consensus ROH with expression. The x axis shows 22 autosomal chromosomes in numerical order. The American Journal of Human Genetics , DOI: ( /j.ajhg ) Copyright © 2015 The American Society of Human Genetics Terms and Conditions
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