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Role of Luteinising Hormone Releasing Hormone (LHRH) Agonists and Hormonal Treatment in the Management of Prostate Cancer  P. Mongiat-Artus, P. Teillac 

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Presentation on theme: "Role of Luteinising Hormone Releasing Hormone (LHRH) Agonists and Hormonal Treatment in the Management of Prostate Cancer  P. Mongiat-Artus, P. Teillac "— Presentation transcript:

1 Role of Luteinising Hormone Releasing Hormone (LHRH) Agonists and Hormonal Treatment in the Management of Prostate Cancer  P. Mongiat-Artus, P. Teillac  European Urology Supplements  Volume 4, Issue 5, Pages 4-13 (July 2005) DOI: /j.eursup Copyright © 2005 Elsevier B.V. Terms and Conditions

2 Fig. 1 Treatment strategies are dependent on the possibility of cure, but overall, LHRH agonists play an important role in the treatment of PCa. European Urology Supplements 2005 4, 4-13DOI: ( /j.eursup ) Copyright © 2005 Elsevier B.V. Terms and Conditions

3 Fig. 2 Overall survival was significantly better in patients who received immediate hormonal therapy as compared to deferred therapy [25]. Adapted with permission, © 1999 Massachusetts Medical Society. All rights reserved. European Urology Supplements 2005 4, 4-13DOI: ( /j.eursup ) Copyright © 2005 Elsevier B.V. Terms and Conditions

4 Fig. 3 Subjective responses achieved by LHRH agonists are equal to those achieved by orchiectomy [58]. LUTS: lower urinary tract symptoms. European Urology Supplements 2005 4, 4-13DOI: ( /j.eursup ) Copyright © 2005 Elsevier B.V. Terms and Conditions

5 Fig. 4 Almost all patients reach serum testosterone castrate levels of ≤50ng/dL in about 3-4 weeks after the first LHRH agonist injection [59–63]. European Urology Supplements 2005 4, 4-13DOI: ( /j.eursup ) Copyright © 2005 Elsevier B.V. Terms and Conditions


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