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Kazunori Yoshida, MD, Satoshi Tobe, MD, Masahito Kawata, MD 

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1 Acquired von Willebrand Disease Type IIA in Patients with Aortic Valve Stenosis 
Kazunori Yoshida, MD, Satoshi Tobe, MD, Masahito Kawata, MD  The Annals of Thoracic Surgery  Volume 81, Issue 3, Pages (March 2006) DOI: /j.athoracsur Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Preoperative immunoblotting analysis. A deficit of von Willebrand factor large multimers is seen indicating type IIA von Willebrand syndrome. Black arrow shows the deficit zone of large multimers (L zone in the A). (A = patient before surgery; L = large multimers; M = middle multimers; N = control subject; S = small multimers; SS = very small multimers.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Postoperative immunoblotting analysis. Protein bands have normalized due to the increase in large multimers. (A = patient after surgery; L = large multimers; M = middle multimers; N = control subject; S = small multimers; SS = very small multimers.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

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