1. Plasma Formed elements Erythrocytes Platelets Leukocytes
Chapter 10: BLOOD!
Plasma
Formed elements
Erythrocytes
Platelets
Leukocytes

2. Separation of Blood Components
Buffy Coat
Centri = center
Centrifuge activity: vial, pencil, string, dirty water

3. Water Solvent for transport. Miscellaneous Nutrients, Wastes,
Plasma
Water Solvent for transport.
Homeostasis, Clotting,
Plasma Proteins
Immunity, Transport
Miscellaneous Nutrients, Wastes,
Gases, Hormones
Salts Homeostasis

4. Formed Elements Leukocytes = white blood cells immunity
Pg 299
Leukocytes = white blood cells immunity
Platelets = clotting
The layer produced by these two types of blood elements is called the “Buffy Coat.”
Buffy Coat

5. Formed Elements Leukocytes: Neutrophils = phagocytes
Pg 299
Leukocytes:
Neutrophils = phagocytes
Eosinophils = kills worms, fights allergies, neutralizes harmful chemicals
Basophils = contain histamine to fight allergies and inflammation.
Buffy Coat
Leuko = white
Cyte = cell

6. Formed Elements Leukocytes:
Pg 299
Leukocytes:
Lymphocytes = immunity B-cells: produces antibodies T-cells: fights tumors and viruses and activate B-cells

7. Formed Elements Leukocytes:
Pg 299
Leukocytes:
5. Monocytes = phagocytes that become macrophages “Clean-up Team” = digests larger cells.
Mono = one

8. Formed Elements Erythrocytes = red blood cells (RBCs) carries oxygen
Pg 299
Erythrocytes = red blood cells (RBCs)
carries oxygen
Hemoglobin = part of erythrocyte that bonds to carries the oxygen and also can transport CO2 waste away
erythro = red

9. Hematopoiesis = production of blood cells
Occurs in bone marrow.
Hemocytoblast = stem cell for blood
Erythropoietin = hormone controlling the production of blood cells.

10. BLOOD
Antigens are tiny receptors on the outside of the blood cell that matches the “type.”
Blood cells have antigens and antibodies.
Antibodies are what the cell doesn’t like (which is anything different from the “type.”)

11. Blood Types Anti-B Anti-A Type B Type A B A Antigens (none) Type AB
Type O
Anti-A and B
none

12. Genetics of Blood type A A A or A i B BB or B i AB O i i pheno-type
genotype
antigen on RBC
antibodies in blood
donation status A
A A or A i
type A antigens on surface of RBC
anti-B antibodies
Receive A or O B
BB or B i
type B antigens on surface of RBC
anti-A antibodies
Receive B or O AB
both type A & type B antigens on surface of RBC
no antibodies
universal recipient O
i i
no antigens on surface of RBC
anti-A & anti-B antibodies
universal donor

13. Rh Factors
Rh comes from the rhesus monkey in which the factor was originally identified.
Rh+ means the RBCs carry the Rh antigen.
If an Rh- person receives Rh+ blood, their immune system will react to the transfusion and the patient’s antibodies will attack and kill the new blood cells.
How could an Rh+ woman became pregnant with an Rh- baby and what would happen to the baby?

14. Bleeding Disorders Thrombocytopenia = not enough platelets to clot.
Liver can’t produce clotting factors due to lack of Vitamin K.
Hemophilia = several inherited bleeding diseases
“Free bleeder” No platelets are present.