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Non Small-Cell Lung Cancer in a 15-Year-Old Nonsmoker
Bindu Koodiyedath, MRCPCH, Anthony Owen, MBChB, Jenny Walker, FRCS, Kim Suvarna, FRCPath, Patricia Fisher, FRCR, Daniel Yeomanson, MRCPCH Journal of Thoracic Oncology Volume 7, Issue 9, Pages e12-e13 (September 2012) DOI: /JTO.0b013e31825ccaaf Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions
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Figure 1 Plain chest radiograph demonstrating left-sided pneumothorax and bulky left mediastinum. Journal of Thoracic Oncology 2012 7, e12-e13DOI: ( /JTO.0b013e31825ccaaf) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions
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Figure 2 Computed tomography thorax demonstrating mediastinal adenopathy (mediastinal window, white arrow) and an endobronchial mass in the left main bronchus (lung window, black arrow). Journal of Thoracic Oncology 2012 7, e12-e13DOI: ( /JTO.0b013e31825ccaaf) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions
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Figure 3 Biopsy (original magnification × 400, haematoxylin & eosin stain) showing lymphoid rich background and pleomorphic poorly defined epithelioid/polygonal cells with bland eosinophilic cytoplasm, somewhat vesicular nuclei, and prominent nucleoli (arrowed). Immunohistochemistry showed weak cytokeratin (MNF116, CK5/6) and EMA reactivity. No reactivity was seen with other keratins (AE1AE3, CAM5.2). Other markers targeting germ cell, lymphoid, and soft tissue neoplasia were negative. Journal of Thoracic Oncology 2012 7, e12-e13DOI: ( /JTO.0b013e31825ccaaf) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions
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