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Children after Allogeneic Hematopoietic Cell Transplantation Can Develop BK Virus Nephropathy: Pilot Data Using Urinary Polyomavirus-Haufen Testing  Benjamin.

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Presentation on theme: "Children after Allogeneic Hematopoietic Cell Transplantation Can Develop BK Virus Nephropathy: Pilot Data Using Urinary Polyomavirus-Haufen Testing  Benjamin."— Presentation transcript:

1 Children after Allogeneic Hematopoietic Cell Transplantation Can Develop BK Virus Nephropathy: Pilot Data Using Urinary Polyomavirus-Haufen Testing  Benjamin Laskin, MD, MS, Harsharan K. Singh, MD, David Witte, MD, Sonata Jodele, MD, Stella M. Davies, MBBS, PhD, Christopher E. Dandoy, MD, MSc, Jens Goebel, MD, Volker Nickeleit, MD  Biology of Blood and Marrow Transplantation  Volume 21, Issue 2, Pages S230-S231 (February 2015) DOI: /j.bbmt Copyright © Terms and Conditions

2 Figure 1 By routine electron microscopy, a large polyomavirus Haufen cast is detected in the urine of a hematopoietic cell transplant recipient. Biology of Blood and Marrow Transplantation  , S230-S231DOI: ( /j.bbmt ) Copyright © Terms and Conditions

3 Figure 2 Kidney autopsy specimen from a hematopoietic cell transplant recipient with detectable urine Haufen. Tissue stained for BK virus using DNA in situ hybridization. Although the tissue is autolyzed, kidney tubules (arrow head) and tubular lumens (arrow) show positive staining for BK virus infected cells,defining polyomavirus nephropathy. Biology of Blood and Marrow Transplantation  , S230-S231DOI: ( /j.bbmt ) Copyright © Terms and Conditions


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