1. Volume 129, Issue 1, Pages 315-320 (July 2005)
Dual Hereditary Jaundice: Simultaneous Occurrence of Mutations Causing Gilbert’s and Dubin-Johnson Syndrome 
Dita Cebecauerova, Tomas Jirasek, Lucie Budisova, Vaclav Mandys, Vladimir Volf, Zorka Novotna, Iva Subhanova, Martin Hrebicek, Milan Elleder, Milan Jirsa 
Gastroenterology 
Volume 129, Issue 1, Pages (July 2005)
DOI: /j.gastro
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2. Figure 1
Liver histology and immunohistology of the index patient. H&E-stained liver tissue with brown granular deposits of lipofuscin (A) gave a PAS-positive reaction (B). The arrow indicates brown lipofuscin granules dispersed within the cytoplasm. (Original magnification ×400.)
Gastroenterology  , DOI: ( /j.gastro )
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3. Figure 2
Confocal laser scanning micrographs with double immunofluorescence staining for CEACAM1 (A and D) and MRP2 (B and E). Cell nuclei are stained with DAPI, and cell borders are highlighted with Nomarski contrast optics (C and F). In the control liver, MRP2 and CEACAM1 colocalize with the canalicular membrane of hepatocytes (C, yellow). In contrast, in the patient’s liver, MRP2 is absent on both canalicular membranes and in cytoplasm of hepatocytes (E and F). Expression of CEACAM1 is not affected (D and F). (Original magnification ×630.)
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2005 American Gastroenterological Association Terms and Conditions

4. Figure 3
Heterozygous mutations detected in exon 10 and 30 of ABCC2/MRP2 gene (A) and a homozygous insertion of TA in the TATAA-box of the UGT1A1 gene promoter (B). The pattern of inheritance of the mutations was determined using AluI RFLP (A, left), AlwNI RFLP (A, right), and fragment analysis (B), respectively.
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2005 American Gastroenterological Association Terms and Conditions