1. Sending Cancer into the Fetal Position
Hannah A. Pizzato, Deepta Bhattacharya 
Cell Stem Cell 
Volume 22, Issue 4, Pages (April 2018)
DOI: /j.stem
Copyright © 2018 Elsevier Inc. Terms and Conditions

2. Figure 1
iPSC Vaccination Promotes a Robust T Cell Response Leading to Tumor Immunity
Mice were vaccinated with either saline (A) or an iPSC and CpG cocktail (B). Vaccinated mice were then injected with breast, skin, or lung cancer cells. Tumors (blue circles) of control mice grew, but those of mice vaccinated with iPSCs did not. The iPSC-vaccinated mice possessed activated T cells reactive to epitopes shared between iPSCs and cancer cells (orange triangles). Upon adoptive transfer of these T cells to a mouse already bearing a tumor, the tumor regressed in response to T cells from iPSC-vaccinated mice but did not do so in response to cells from control mice.
Cell Stem Cell  , DOI: ( /j.stem )
Copyright © 2018 Elsevier Inc. Terms and Conditions