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Randomized Phase II Study Comparing Prophylactic Cranial Irradiation Alone to Prophylactic Cranial Irradiation and Consolidative Extracranial Irradiation.

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Presentation on theme: "Randomized Phase II Study Comparing Prophylactic Cranial Irradiation Alone to Prophylactic Cranial Irradiation and Consolidative Extracranial Irradiation."— Presentation transcript:

1 Randomized Phase II Study Comparing Prophylactic Cranial Irradiation Alone to Prophylactic Cranial Irradiation and Consolidative Extracranial Irradiation for Extensive- Disease Small Cell Lung Cancer (ED SCLC): NRG Oncology RTOG 0937  Elizabeth M. Gore, MD, Chen Hu, PhD, Alexander Y. Sun, MD, Daniel F. Grimm, MS, Suresh S. Ramalingam, MD, Neal E. Dunlap, MD, Kristin A. Higgins, MD, Maria Werner-Wasik, MD, Aaron M. Allen, MD, Puneeth Iyengar, MD, PhD, Gregory M.M. Videtic, MD, Russell K. Hales, MD, Ronald C. McGarry, MD, James J. Urbanic, MD, Anthony T. Pu, MD, Candice A. Johnstone, MD, Volker W. Stieber, MD, Rebecca Paulus, BS, Jeffrey D. Bradley, MD  Journal of Thoracic Oncology  Volume 12, Issue 10, Pages (October 2017) DOI: /j.jtho Copyright © Terms and Conditions

2 Figure 1 CONSORT flow diagram. Abbreviations: PCI, prophylactic cranial irradiation; PCI+CRT, prophylactic cranial irradiation plus consolidative radiation therapy; CBC, complete blood count; PET, positron emission tomography; CT, computed tomography; CNS, central nervous system; RT, radiation therapy. Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © Terms and Conditions

3 Figure 2 Overall survival. Abbreviations: PCI, prophylactic cranial irradiation; PCI+RT, prophylactic cranial irradiation plus radiation therapy; CI, confidence interval. Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © Terms and Conditions

4 Figure 3 Time to progression. Abbreviations: PCI, prophylactic cranial irradiation; PCI+RT, prophylactic cranial irradiation plus radiation therapy. Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © Terms and Conditions


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