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Memantine for prevention of spinal cord injury in a rabbit model

Published byKrista Lichtenberg Modified over 5 years ago

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Presentation on theme: "Memantine for prevention of spinal cord injury in a rabbit model"— Presentation transcript:

1 Memantine for prevention of spinal cord injury in a rabbit model
Marek Ehrlich, MDa, Erich Knolle, MDb, Ruxandra Ciovica, MDa, Peter Böck, MDc, Edvin Turkof, MDa, Martin Grabenwöger, MDa, Fabiola Cartes-Zumelzu, MDa, Alfred Kocher, MDa, Helmut Pockberger, MDd, W.Christopher Fang, MDa, Ernst Wolner, MDa, Michael Havel, MDa  The Journal of Thoracic and Cardiovascular Surgery  Volume 117, Issue 2, Pages (February 1999) DOI: /S (99) Copyright © 1999 Mosby, Inc. Terms and Conditions

2 Fig. 1 Cross section of the lumbar spinal cord in an animal treated with memantine. Well-preserved, normal-looking motor neurons are seen. Perikarya are polygonal with cytoplasmic extensions. The cytoplasm stains violet; it contains ample Nissl substance as clumps of basophilic material. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (99) ) Copyright © 1999 Mosby, Inc. Terms and Conditions

3 Fig. 2 Cross section of the lumbar spinal cord in a control animal. Edema and vacuolization are prominent in anterior horn motor neurons. Cellular shape is ovoid to round, and Nissl substance is highly dispersed or no longer present. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (99) ) Copyright © 1999 Mosby, Inc. Terms and Conditions

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