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S. So¨derstro¨m, G. Nyberg, M.F. O’Rourke, J. Sellgren, J. Pontén 

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Presentation on theme: "S. So¨derstro¨m, G. Nyberg, M.F. O’Rourke, J. Sellgren, J. Pontén "— Presentation transcript:

1 Can a clinically useful aortic pressure wave be derived from a radial pressure wave?†  
S. So¨derstro¨m, G. Nyberg, M.F. O’Rourke, J. Sellgren, J. Pontén  British Journal of Anaesthesia  Volume 88, Issue 4, Pages (April 2002) DOI: /bja/ Copyright © 2002 British Journal of Anaesthesia Terms and Conditions

2 Fig 1 An example of pulse waves during peak effect of the Valsalva manoeuvre, displaying the close correlation between measured (thin line) and synthesized aortic (SA; bold line) waveforms compared with the radial waveform (dotted line). Since the SA waveform is constructed from the radial wave they appear synchronous in time. British Journal of Anaesthesia  , DOI: ( /bja/ ) Copyright © 2002 British Journal of Anaesthesia Terms and Conditions

3 Fig 2 Bland–Altman plots showing the differences between systolic pressure during Valsalva in the measured aortic waveform (MA) and radial waveform (MR), left panel, and the differences in systolic pressure during Valsalva between MA and synthesized aortic waveform (SA), right panel. The dotted lines display mean and 2sd. British Journal of Anaesthesia  , DOI: ( /bja/ ) Copyright © 2002 British Journal of Anaesthesia Terms and Conditions

4 Fig 3 Ensemble averaged pulse waves from all points of measurement in all patients. The control period is represented by a thin line, midazolam by a dotted line and nitroglycerin by a bold line. Note the disappearance of the late systolic shoulder and the minor decrease in systolic pressure in the radial artery during nitroglycerin, while both the synthesized and measured aortic pulse waves display a marked and uniform fall in systolic pressure, and the same wave contour. British Journal of Anaesthesia  , DOI: ( /bja/ ) Copyright © 2002 British Journal of Anaesthesia Terms and Conditions

5 Fig 4 Bland–Altman plots displaying the differences between measured aortic waveform (MA) and measured radial waveform (MR) (left panel) and between MA and synthesized aortic waveform (SA) (right panel) for systolic and diastolic pressures (a); end systolic pressures (b); augmentation index (c); and systolic and diastolic areas (d). True aortic systolic pressure was underestimated by SA and diastolic pressure overestimated, but variation in systolic pressure, especially with nitroglycerin, was reduced compared with MR. In a, b and c, circles indicate controls, squares indicate midazolam and triangles indicate nitroglycerin intervention. In d, squares indicate systolic area and circles indicate diastolic area. Dotted lines display mean and 2sd. British Journal of Anaesthesia  , DOI: ( /bja/ ) Copyright © 2002 British Journal of Anaesthesia Terms and Conditions


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