1. VEGF and its Receptors are Expressed in a Pediatric Angiosarcoma in a Patient with Aicardi's Syndrome 
Elizabeth R. McLaughlin, Jack L. Arbiser 
Journal of Investigative Dermatology 
Volume 114, Issue 6, Pages (June 2000)
DOI: /j x
Copyright © 2002 The Society for Investigative Dermatology, Inc Terms and Conditions

2. Figure 1
Clinical progression of angiosarcoma. (A) Photograph of vascular anomaly on left foot at 10 mo of age; (B) dramatic change in lesion 1 mo later.
Journal of Investigative Dermatology  , DOI: ( /j x)
Copyright © 2002 The Society for Investigative Dermatology, Inc Terms and Conditions

3. Figure 2
Histology and in situ hybridization of tumor tissue. (A) Histology of angiosarcoma; hematoxylin and eosin. (a) A solid focus of less differentiated angiosarcoma cells. (b) Area of angiosarcoma exhibiting a higher level of differentiation through production of primitive vascular channels lined by neoplastic endothelial cells. Scale bar: 50 μm. (B) In situ hybridization of angiosarcoma for expression of (a) VPF/VEGF, (b) VEGFR-1, and (c) VEGFR-2. Scale bar: 50 μm. (C) In situ hybridization of angiosarcoma for expression of (a) angiopoietin-1, (b) angiopoietin-2, (c) Tie1, (d) Tie2, (e) angiopoietin-4. Scale bar: 50 μm.
Journal of Investigative Dermatology  , DOI: ( /j x)
Copyright © 2002 The Society for Investigative Dermatology, Inc Terms and Conditions