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Baseline measure of health-related quality of life (Functional Assessment of Cancer Therapy-Esophagus) is associated with overall survival in patients.

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Presentation on theme: "Baseline measure of health-related quality of life (Functional Assessment of Cancer Therapy-Esophagus) is associated with overall survival in patients."— Presentation transcript:

1 Baseline measure of health-related quality of life (Functional Assessment of Cancer Therapy-Esophagus) is associated with overall survival in patients with esophageal cancer  Biniam Kidane, MD, MSc, Joanne Sulman, MSW, Wei Xu, PhD, Qin Quinn Kong, MSc, Rebecca Wong, MBChB, MSc, Jennifer J. Knox, MD, MSc, Gail E. Darling, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 151, Issue 6, Pages (June 2016) DOI: /j.jtcvs Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 Histogram of FACT-E and ECS distributions. Histogram depicting the distribution of (A) FACT-E scores and (B) ECS scores. FACT-E, Functional Assessment of Cancer Therapy-Esophagus; ECS, esophageal cancer subscale. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

3 Figure 2 Low baseline FACT-E and ECS associated with worse overall survival. A, Kaplan–Meier curve showing results of Cox regression analysis with baseline FACT-E stratified into low and high FACT-E groups. B, Kaplan–Meier curve showing results of Cox regression analysis with baseline ECS stratified into low and high ECS groups. Solid lines represent the observed survival curves, and dotted lines represent the 95% CIs. Low baseline FACT-E and ECS are associated with worse overall survival. HR, Hazard ratio; FACT-E, Functional Assessment of Cancer Therapy-Esophagus; ECS, esophageal cancer subscale. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

4 Figure 3 Increasing FACT-E and ECS quartiles associated with increasing overall survival. Kaplan–Meier curve showing results of Cox regression analysis with baseline (A) FACT-E and (B) ECS stratified into quartile groups. Numbering of quartiles is such that HRQOL is increasing as quartile number increases (ie, quartile 1 has lowest HRQOL). Increasing FACT-E and ECS quartiles are associated with increasing overall survival. FACT-E, Functional Assessment of Cancer Therapy-Esophagus; ECS, esophageal cancer subscale. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

5 Lower baseline HRQOL (FACT-E) is associated with poorer survival.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions


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