1. Blood Sugar Regulation

2. Pancreas

3. Pancreas

4. Pancreas Two cell types to produce: exocrine acini produce:
islets of Langerhans produce:
1 – 2% of pancreas are the islets of Langerhans

5. Islets of Langerhans Two hormones are produced: beta cells:
alpha cells:
blue = cell nuclei
green = insulin
red = glucagon

6. Insulin Function When is insulin released? after eating hyperglycemia
beta cells
decreased blood sugar
cellular signals for insulin release
increased glucose uptake
glycogen production in liver

7. Glucagon Function What does glucagon do? breaks down glycogen
hypoglycemia
alpha cells
increased blood sugar
cellular signals for glucagon release
glucose release from liver
glucose production in liver

8. Blood Sugar Diseases Three types of diabetes:
Diabetes Mellitus - Type 1
Diabetes Mellitus - Type 2
Diabetes Insipidus

9. Diabetes Mellitus – Type I
also known as:
Cause
Symptoms
Treatment

10. Diabetes Mellitus – Type II
formerly known as:
Cause
Symptoms
Treatment

11. Diabetes Insipidus
Cause
Symptoms
Treatment

12. Canadian Connection Frederick Banting & Charles Best
Nobel Prize – 1923
insulin isolation
tied off ducts to digestive tract
cell producing digestive enzymes shrivelled
only islets of Langerhans remained