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Heavy Smoking Before Coronary Surgical Procedures Affects the Native Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 Gene Expression in Saphenous.

Published byΜελπομένη Ζαφειρόπουλος Modified over 5 years ago

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Presentation on theme: "Heavy Smoking Before Coronary Surgical Procedures Affects the Native Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 Gene Expression in Saphenous."— Presentation transcript:

1 Heavy Smoking Before Coronary Surgical Procedures Affects the Native Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 Gene Expression in Saphenous Vein Conduits  Sun Yongxin, MD, Ding Wenjun, MD, Wei Qiang, MD, Shi Yunqing, MD, Zhu Liming, MD, Wang Chunsheng, MD  The Annals of Thoracic Surgery  Volume 95, Issue 1, Pages (January 2013) DOI: /j.athoracsur Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Immunostaining of matrix metalloproteinases (MMPs)/tissue inhibitors of metalloproteinases (TIMPs) in saphenous vein (SV) conduits (diaminobenzidine stain, original magnification ×100). The representative immunohistochemical analysis shows MMP-2, MMP-9, TIMP-1, and TIMP-2 immunostaining in SV conduits of patients with different smoking status. The Annals of Thoracic Surgery  , 55-61DOI: ( /j.athoracsur ) Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Tissue MMP-2, MMP-9, TIMP-1, and TIMP-2 protein levels in saphenous vein (SV) conduits. A representative image of Western blotting shows the tissue MMP-2, MMP-9, TIMP-1, and TIMP-2 protein levels in SVs of different groups. (MMP = matrix metalloproteinase; MW = molecular weight; TIMP = tissue inhibitors of metalloproteinases.) The Annals of Thoracic Surgery  , 55-61DOI: ( /j.athoracsur ) Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

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