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Allergen reference doses for precautionary labeling (VITAL 2

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Presentation on theme: "Allergen reference doses for precautionary labeling (VITAL 2"— Presentation transcript:

1 Allergen reference doses for precautionary labeling (VITAL 2
Allergen reference doses for precautionary labeling (VITAL 2.0): Clinical implications  Katrina J. Allen, MD, PhD, FAAAAI, Benjamin C. Remington, BS, Joseph L. Baumert, PhD, Rene W.R. Crevel, DIBT, Geert F. Houben, PhD, Simon Brooke-Taylor, PhD, Astrid G. Kruizinga, MSc, Steve L. Taylor, PhD  Journal of Allergy and Clinical Immunology  Volume 133, Issue 1, Pages (January 2014) DOI: /j.jaci Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 Dose-distribution models for individual thresholds (expressed as milligrams of protein) based on allergic patients for diagnostic studies, threshold studies, and immunotherapy studies: A, peanut; B, milk. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3 Fig 2 Dose-distribution models for individual thresholds (expressed as milligrams of protein) based on geographic location: A, peanut; B, milk. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

4 Fig 3 Probability distribution models for individual thresholds (expressed as milligrams of protein) based on age of the allergic patient at challenge: A, peanut; B, hazelnut. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

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