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Published byEliška Bartošová Modified over 5 years ago
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Understanding Protein-Protein Interactions on Biosensor Surfaces
Vincent Chang Mentor: Lisa Plucinski
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Overview Learn how to use the COMSOL application
Use COMSOL models to understand the fundamentals of reaction kinetics and surface binding
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Program Used COMSOL Multiphysics 5.1 Transport and Adsorption
Modeling phenomena of surface binding in different dimensions (3D to 2D).
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Progress Creating a 2D model that displays the concentration of the reacting species at various areas of the surface through time Understanding the physics behind why surface concentration of reacting species vary through position and time Understanding reaction rates on surface binding through time
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Future Goals Obtain experimental data for biotin-streptavidin binding on a biosensor with a microfluidic channel Explore how various experimental parameters impact protein-binding kinetics Explore methods to fit experimental data to models
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Sources All information is received through COMSOL Multiphysics 5.1 Transport and Adsorption
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