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Necrotizing enterocolitis is one disease with many origins and potential means of prevention
Phillip V. Gordon, Jonathan R. Swanson Pathophysiology Volume 21, Issue 1, Pages (February 2014) DOI: /j.pathophys Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions
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Fig. 1 Summation/consolidation of data about NEC, including time of presentation, percent mortality and incidence of disease stratified by gestational age. Left-sided y-axis equals day of onset indicated by the sphere centers. The sphere diameters indicate the percent of total NEC that presented on that day of life (mean for the gestational age group), and correlate with the x-axis below. The gray columns indicate the percent mortality (right side y-axis). Data for the extrapolations in this figure are based upon summarized data from Refs. [30–33]. In cases where precise data was unavailable in the units needed (for example, if the data were available by birth weight instead of gestational age), the data were extrapolated using the assumption that the population as a whole was appropriate for gestational age and the datasets were representative of a common disease entity. For example, two single center reports were used to overlay the timing of NEC onset onto the national dataset of incidence and mortality. Pathophysiology , 13-19DOI: ( /j.pathophys ) Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions
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Fig. 2 Schematic of early versus late risk factors for necrotizing enterocolitis. Pathophysiology , 13-19DOI: ( /j.pathophys ) Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions
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Fig. 3 Schematic depicting predicted subgroup overlap between necrotizing enterocolitis subsets. Pathophysiology , 13-19DOI: ( /j.pathophys ) Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions
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