1. Veggies and Intact Grains a Day Keep the Pathogens Away
Francesca S. Gazzaniga, Dennis L. Kasper 
Cell 
Volume 167, Issue 5, Pages (November 2016)
DOI: /j.cell
Copyright © 2016 Elsevier Inc. Terms and Conditions

2. Figure 1
Effects of Dietary Fiber and Gut Microbiota on the Colonic Mucus Barrier and Pathogen Susceptibility
Mice colonized with a synthetic microbiota and fed a fiber-rich diet have more fiber-degrading bacteria and a thick mucus lining and are protected from Citrobacter rodentium infection. In contrast, mice fed a fiber-free diet have an outgrowth of mucus-degrading bacteria and a thin mucus layer and are susceptible to C. rodentium infection. Germ-free mice on either a fiber-rich or a fiber-free diet have a thin mucus layer but are protected from C. rodentium infection. This study suggests that, on a fiber-free diet, mucus-degrading bacteria outcompete fiber-degrading bacteria, erode the mucus layer, and promote susceptibility to C. rodentium infection.
Cell  , DOI: ( /j.cell )
Copyright © 2016 Elsevier Inc. Terms and Conditions