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Sildenafil augments the effect of inhaled nitric oxide for postoperative pulmonary hypertensive crises  Andrew M. Atz, MDa, Amy K. Lefler, PharmDb, David.

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Presentation on theme: "Sildenafil augments the effect of inhaled nitric oxide for postoperative pulmonary hypertensive crises  Andrew M. Atz, MDa, Amy K. Lefler, PharmDb, David."— Presentation transcript:

1 Sildenafil augments the effect of inhaled nitric oxide for postoperative pulmonary hypertensive crises  Andrew M. Atz, MDa, Amy K. Lefler, PharmDb, David L. Fairbrother, MDa, Walter E. Uber, PharmDb, Scott M. Bradley, MDc  The Journal of Thoracic and Cardiovascular Surgery  Volume 124, Issue 3, Pages (September 2002) DOI: /mtc Copyright © 2002 American Association for Thoracic Surgery Terms and Conditions

2 Fig. 1 Continuous traces of heart rate, blood pressure (systolic, mean, and diastolic), and pulmonary artery pressure (systolic, mean, and diastolic) recorded every minute. Despite treatment with NO at 20 ppm for 4 days, the patient had persistently elevated pulmonary artery pressure. A 0.3 mg/kg dose of sildenafil given at the cursor caused additional selective pulmonary vasodilation. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /mtc ) Copyright © 2002 American Association for Thoracic Surgery Terms and Conditions


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