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Robert Kleta, MD, PhD, Scott C

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1 Keratopathy of Multiple Myeloma Masquerading as Corneal Crystals of Ocular Cystinosis 
Robert Kleta, MD, PhD, Scott C. Blair, MD, Isa Bernardini, MEd, Muriel I. Kaiser-Kupfer, MD, William A. Gahl, MD, PhD  Mayo Clinic Proceedings  Volume 79, Issue 3, Pages (March 2004) DOI: / Copyright © 2004 Mayo Foundation for Medical Education and Research Terms and Conditions

2 Figure 1 A, Bone marrow aspirate packed with plasma cells (hematoxylin-eosin, original magnification ×300). Photomicrograph courtesy of Richard Zellmer, MD, Riverside Methodist Hospital, Columbus, Ohio. B, Narrow-beam slit-lamp biomicroscopy shows that crystals are located exclusively in the epithelium and most superficial stromal layer of the cornea. Centrally, the cornea appears slightly thicker and the crystals slightly more prominent. C, Broad-beam slit-lamp biomicroscopy of the left eye shows diffuse, very small corneal crystals that are not reflective. D, Broad-beam slit-lamp biomicroscopy of the cornea of an adult patient with ocular cystinosis. Crystals are reflective and located throughout the corneal epithelium and entire stromal layer. Photographs of the eyes courtesy of Patrick Ciatto, National Institutes of Health, Bethesda, Md. Mayo Clinic Proceedings  , DOI: ( / ) Copyright © 2004 Mayo Foundation for Medical Education and Research Terms and Conditions


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