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Facilitator: Pawin Puapornpong
Journal club 5 Facilitator: Pawin Puapornpong
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Pediatric Outcome after Maternal Cancer Diagnosed during Pregnancy
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Background Method Result Discussion Conclusion Background Data on the long-term outcome of children who are exposed to maternal cancer with or without treatment during pregnancy are lacking. Cancer treatment during pregnancy exposes the fetus to potentially toxic substances
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Background:Objective
Method Result Discussion Conclusion Background:Objective Evaluated children who had prenatal exposure to maternal cancer combined with control group.
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Reserch question P(Patient) : Children born to mothers with cancer
Background Method Result Discussion Conclusion Reserch question P(Patient) : Children born to mothers with cancer I(Intervention) :Cancer treatment C(control) : Children from born to healthy mothers O(Outcome) : general health, cognitive developmental, cardiac abnormalities
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Method Type of multicenter case–control pro-retrospective study
Background Method Result Discussion Conclusion Method Type of multicenter case–control pro-retrospective study Conducted inInternational Network on Cancer, Infertility,and Pregnancy. wikimapia.org
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Method, Population:Inclusion criteria
Background Method Result Discussion Conclusion Method, Population:Inclusion criteria Children who had mothers that cancer was diagnosed during pregnancy With or without treatment
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Method, Population:Control group
Background Method Result Discussion Conclusion Method, Population:Control group children born to healthy mothers uncomplicated pregnancies and deliveries
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Background Method Result Discussion Conclusion Method
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18 36 36 Method general health examinations
Background Method Result Discussion Conclusion Method general health examinations cognitive developmental general health examinations cognitive developmental ECG+-Echocardiography talkingheads.net.au 18 36 Bayley II mental developmental 36
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Background Method Result Discussion Conclusion Statistical analysis Analyse by mean and SDs and compared using Mann–Whitney U test ,chi-square and Fisher’s exact test
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Result:Perinatal Outcome
Background Method Result Discussion Conclusion Result:Perinatal Outcome
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Result:Characteristics of the Children
Background Method Result Discussion Conclusion Result:Characteristics of the Children 4 11 24 95
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Result:Cognitive Development
Background Method Result Discussion Conclusion Result:Cognitive Development Developmental Assessment Scales for Indian Infants;
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Result:Cognitive Development
Background Method Result Discussion Conclusion Result:Cognitive Development Developmental Assessment Scales for Indian Infants;
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Result:cardiac assessment
Background Method Result Discussion Conclusion Result:cardiac assessment
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Discussion:Strength Mutiple follow up outcome Background Method Result
Conclusion Discussion:Strength Mutiple follow up outcome
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Discussion:Limitation
Background Method Result Discussion Conclusion Discussion:Limitation cannot be extrapolated to all chemotherapeutic drugs follow-up period was too short
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Background Method Result Discussion Conclusion Conclusion Prenatal exposure to maternal cancer did not impair the cognitive, cardiac, or general development of children in early childhood
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