1. Physiological effects of transfer

2. Key points Acceleration / deceleration Noise / vibration / temperature
Effects of altitude.
Oxygen
Pressure

3. Acceleration / deceleration
Newton’s first law of motion
‘An object either remains at rest or continues to move at a constant velocity, unless acted upon by a net force.’
This will have multiple effects

4. Cardiovascular effects
Veins are floppy, changes in velocity will cause shifts of blood within the vascular system.
For a standard ambulance layout:
When the ambulance accelerates then there will be a tendency for the patient's blood to move towards their feet.
When the ambulance decelerates there will be a tendency for the patient's blood to move towards their head.
Demo using ¾ full 2 litre bottle.
In health, the baroreceptor and vasoconstrictor reflexes will limit these effects, but such reflexes are often obtunded or absent in the critically ill due to illness or drug therapy. Consequently, hypotension may be profound, particularly if preload is already reduced due to hypovolaemia or positive pressure ventilation.

5. Ambulance accelerates
Blood moves to feet
Ambulance decelerates
Blood moves to head

6. Ambulance acceleration
Blood moving towards patient’s feet: Effects documented in military aviation studies
Grey out
Black out
LoC
Difficult to assess what is happening in a sedated patient
The neurological effects of +Gz exposure have been well documented through military aviation studies [6,7], and although these effects are unlikely during patient transfers it may be impossible to assess their effects accurately in an unconscious patient. The pooling of blood in the lower body and feet results in reduced blood supply to the brain. In health, progressive +Gz exposure will lead to loss of peripheral vision (grey-out), loss of vision with consciousness maintained (black-out) and complete loss of consciousness (G-LOC). Significantly, seizures have been reported on return of blood supply to the brain after cessation of these forces. Although the symptoms of reduced supply may not be recognized in an unconscious patient, it is important to have an appreciation of the risks this may pose and also of the possibility of convulsions once this situation reverses.

7. Ambulance deceleration
Blood moves towards patient’s head
Normal compensatory mechanisms would adjust for this, but with cardiac dysfunction or if compensatory mechanisms are absent, this may result in cardiac dysrhythmias, pulmonary oedema and even cardiac arrest.
But, the most important effect is to increase Intracranial Pressure.
The effects of -1Gz are those experienced when hanging upside-down. Prolonged exposure to this or higher forces has resulted in a condition of ‘red-out’ whereby vision becomes red due to blood engorgement or the lower eyelid being forced over the pupil. Haemorrhages have been reported in both retina and brain following such forces,
ICP increase. This can have potentially devastating effects in patients with critical brain injury and existing compromised cerebral blood flow. In such situations, an increase in ICP can result in critical reduction in blood flow resulting in cerebral ischaemia.

8. Prevention Limit hard braking Head-up tilt during transfer.
Deceleration is likely to be sharper than acceleration and so cause greater physiology derangements – a head up position will limit these.
Full patients travel better *
* Small print – important exception with vascular emergencies
May be needed
Generally better
Ambulances can break sharper than they can accelerate

9. Also,
Ambulance deceleration will cause stomach contents to move towards patient’s head with increased risk of gastro-oesophageal reflux and aspiration
Aspirate NG / free drainage
Acceleration / deceleration potentially have an axial loading effect on the vertebrae
Again, smooth transfers are generally best

10. Safety - staff
You will continue at a constant velocity if the ambulance is suddenly decelerated by an external force – such as a brick wall.
Unsecured objects(e.g. a syringe driver)will continue at a constant velocity if the ambulance comes to a sudden halt – possibly until they hit you!
Seat belts!
ICS insurance

11. Other factors with physiological effects
Noise
Vibration
Temperature
Dehydration? – HMEs
The damaging effects of vibration can be reduced by paying meticulous attention to padding and protecting any areas of the patient in contact with hard objects. The most common temperature consideration is that of hypothermia,

12. Summary Acceleration and deceleration have physiological effects
Also consider vibration and temperature
Aero-medical transfers have complex effects and proper training is essential