1. Airway TGF-β1 and oxidant stress in children with severe asthma: Association with airflow limitation 
Sheena D. Brown, PhD, MSCR, Katherine M. Baxter, BS, Susan T. Stephenson, PhD, Annette M. Esper, MD, Lou Ann S. Brown, PhD, Anne M. Fitzpatrick, PhD, MSCR 
Journal of Allergy and Clinical Immunology 
Volume 129, Issue 2, Pages e8 (February 2012)
DOI: /j.jaci
Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2. Fig 1
Total and active (free) TGF-β1 concentrations in the BAL supernatant (A and B, respectively) and ELF (C and D, respectively) of atopic adult control subjects (AC), children with mild-to-moderate atopic asthma (MMA), and children with severe atopic asthma (SA). Horizontal lines represent the median. P values were obtained after natural logarithmic transformation.
Journal of Allergy and Clinical Immunology  , e8DOI: ( /j.jaci )
Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3. Fig 2
Airway macrophage (AM) protein expression of TGF-β1 measured by means of ELISA (A) and immunofluorescence (B) in atopic adult control subjects (AC), children with mild-to-moderate atopic asthma (MMA), and children with severe atopic asthma (SA). Airway macrophage mRNA gene expression relative to atopic adult control subjects is shown in (C) as 2−ΔΔCt values. In Fig 2, A and B, horizontal lines represent the median, and P values were obtained after natural logarithmic transformation. In Fig 2, C, horizontal lines represent the mean. RFU, Relative fluorescent units.
Journal of Allergy and Clinical Immunology  , e8DOI: ( /j.jaci )
Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

4. Fig 3
Concentrations of IL-13, 8-isoprostanes, and malondialdehyde (MDA) in the BAL fluid (A-C, respectively) and ELF (D-F, respectively) of atopic adult control subjects (AC), children with mild-to-moderate atopic asthma (MMA), and children with severe atopic asthma (SA). IL-13 concentrations were undetectable in 8 atopic adult control subjects. Horizontal lines represent the median. P values were obtained after natural logarithmic transformation.
Journal of Allergy and Clinical Immunology  , e8DOI: ( /j.jaci )
Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

5. Fig 4
Scatter plots with regression lines depicting the relationship between total TGF-β1 and IL-13, 8-isoprostane, and malondialdehyde (MDA) concentrations in the BAL supernatant (A-C) and ELF (D-F) of children with mild-to-moderate and severe asthma.
Journal of Allergy and Clinical Immunology  , e8DOI: ( /j.jaci )
Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

6. Fig E1
Scatter plots with regression lines depicting the association between total airway macrophage (AM) TGF-β1 concentrations and total and active (free) TGF-β1 concentrations in the BAL supernatant (A and B, respectively) and ELF (panels C and D, respectively).
Journal of Allergy and Clinical Immunology  , e8DOI: ( /j.jaci )
Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

7. Fig E2
Total and active (free) TGF-β1 concentrations in the BAL fluid (A and B, respectively) and ELF (C and D, respectively) according to race (white versus nonwhite). Data are stratified by mild-to-moderate asthma (MMA) and severe asthma (SA). Race was not significantly or consistently associated with TGF-β1 concentrations within the severity strata.
Journal of Allergy and Clinical Immunology  , e8DOI: ( /j.jaci )
Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions