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Cardiac outcome in classic infantile Pompe disease after 13 years of treatment with recombinant human acid alpha-glucosidase  Carine I. van Capelle, Esther.

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Presentation on theme: "Cardiac outcome in classic infantile Pompe disease after 13 years of treatment with recombinant human acid alpha-glucosidase  Carine I. van Capelle, Esther."— Presentation transcript:

1 Cardiac outcome in classic infantile Pompe disease after 13 years of treatment with recombinant human acid alpha-glucosidase  Carine I. van Capelle, Esther Poelman, Ingrid M. Frohn-Mulder, Laurens P. Koopman, Johanna M.P. van den Hout, Luc Régal, Bjorn Cools, Wim A. Helbing, Ans T. van der Ploeg  International Journal of Cardiology  Volume 269, Pages (October 2018) DOI: /j.ijcard Copyright © 2018 The Authors Terms and Conditions

2 Fig. 1 Left ventricular cardiac dimensions over time.
A) LVMI Z-scores B) LVPWd Z-scores C) LVMI raw scores D) LVM raw scores. Each of the 14 patients is represented by a different line. The dashed grey lines represent the upper and lower limit of normal (Z-score of +2 and −2) and normal value (Z-score of 0). International Journal of Cardiology  , DOI: ( /j.ijcard ) Copyright © 2018 The Authors Terms and Conditions

3 Fig. 2 Echocardiographic parasternal long axis view of patient 9.
Echocardiographic parasternal long axis view of patient 9 at A) baseline and B) after 5 years of treatment. Note the major difference in both septal and posterior wall thickness. International Journal of Cardiology  , DOI: ( /j.ijcard ) Copyright © 2018 The Authors Terms and Conditions


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