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The Short History of DNA (SNOWBALL FIGHT. ) Modified by D

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1 The Short History of DNA (SNOWBALL FIGHT. ) Modified by D
The Short History of DNA (SNOWBALL FIGHT!!!) Modified by D. Dailey Hewitt-Trussville High School From

2 Searching for Genetic Material
WHO AM I (1868): discovered DNA Isolated something new from the nuclei of eukaryotic cells of white blood cells Later called DNA!!!

3 Searching for Genetic Material
WHO AM I (1928): Studied effects of virulent (virus-causing) bacteria vs. nonvirulent bacteria injected into mice Used transformation: Inserted foreign DNA and changed protein/ trait believed that the transforming agent was an inheritance molecule.

4 WHO AM I Experiment Used the Pneumococcus bacteria Include2 types:
a virulent S strain with a Smooth coat kills mice a non-virulent R Rough strain does not kill mice. Heat destroys (kills) living cells!!! When heated Smooth (harmful) cells (DEAD) are mixed with living Rough (benign) cells and injected into mice, the mouse dies.

5 Discovering the Structure of DNA
WHO AM I (1950) Discovered a 1:1 ratio of adenine to thymine and guanine to cytosine in DNA samples from a variety of organisms.

6 Discovering the structure of DNA
WHO AM I (1952) Photographed DNA using x-ray crystallography Worked with another scientists named WHO AM I Awarded the 1962 Nobel Prize for Physiology or Medicine with Watson and Crick

7 Discovering the structure of DNA
Photo 51 WHO AM I (1952) Obtained sharp X-ray diffraction photographs of DNA (Photo 51) Watson and Crick used her data  revealed its helical shape Watson and Crick went on to win Nobel Prize (1962) for their DNA model

8 Searching for Genetic Material
WHO AM I (1952) Confirmed DNA was genetic material Used bacteriophages (viruses) HYPOTHESIZED DNA, not protein, is the hereditary material

9 Searching for Genetic Material WHO AM I Experiment

10 Discovering the structure of DNA
WHO AM I (1953) Discovered double helix structure Solved the three-dimensional structure of the DNA molecule


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