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Synaptopodin expression in idiopathic nephrotic syndrome of childhood

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Presentation on theme: "Synaptopodin expression in idiopathic nephrotic syndrome of childhood"— Presentation transcript:

1 Synaptopodin expression in idiopathic nephrotic syndrome of childhood
Tarak Srivastava, Robert E. Garola, Joan M. Whiting, Uri S. Alon  Kidney International  Volume 59, Issue 1, Pages (January 2001) DOI: /j x Copyright © 2001 International Society of Nephrology Terms and Conditions

2 Figure 1 Synaptopodin expression in nonsclerosed glomerulus in (A) normal kidney [area of staining, 44.6%; luminance gray value (GV), 86.5], (B) minimal change disease (area of staining, 27.6%; luminance GV, 117.5), (C) focal segmental glomerulosclerosis (area of staining, 1.9%; luminance GV, 160.5), and (D) congenital nephrotic syndrome of the Finnish type (area of staining, 1.5%; luminance GV, 158.7). Immunohistochemistry staining using diaminobenzidine as chromogen is shown (×400). Kidney International  , DOI: ( /j x) Copyright © 2001 International Society of Nephrology Terms and Conditions

3 Figure 2 Box plot distribution of data for synaptopodin expression by (A) luminance gray value (GV) and (B) percentage of glomerular area in nonsclerosed glomeruli in normal, minimal change disease (MCD), diffuse mesangial hypercellularity (DMH), focal segmental glomerulosclerosis (FSGS), and congenital nephrotic syndrome of the Finnish type (CNF). Kidney International  , DOI: ( /j x) Copyright © 2001 International Society of Nephrology Terms and Conditions

4 Figure 3 Box plot distribution of data for synaptopodin expression by (A) luminance gray value (GV) and (B) percentage of glomerular area in nonsclerosed glomeruli in group A (steroid ± cyclophosphamide responsive) and group B (steroid resistant or dependent requiring additional immunosuppressive therapy). Outliers are shown as small circles. Kidney International  , DOI: ( /j x) Copyright © 2001 International Society of Nephrology Terms and Conditions


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