1. Anoxic depolarization of rat hippocampal slices is prevented by thiopental but not by propofol or isoflurane 
R. Sasaki, K. Hirota, S.H. Roth, M. Yamazaki 
British Journal of Anaesthesia 
Volume 94, Issue 4, Pages (April 2005)
DOI: /bja/aei077
Copyright © 2005 British Journal of Anaesthesia Terms and Conditions

2. Fig 1
Base-line trace of the field potential in the stratum pyramidale of CA1 before, during and after 3 min anoxia in the absence of anaesthetics and in the presence of thiopental 2×10−4 M, propofol 2×10−4 M and isoflurane 1.5 vol%. Representative examples show population spikes recorded in CA1 region evoked by stimulation of the Schaffer collateral before, during and after anoxia at each condition. The arrow indicates anoxic depolarization.
British Journal of Anaesthesia  , DOI: ( /bja/aei077)
Copyright © 2005 British Journal of Anaesthesia Terms and Conditions

3. Fig 2
Incidence of AD induced by 3 min anoxia in each of the experimental groups. The incidence of AD was significantly lower in the group treated with thiopental 2×10−4 M (n=19) than in the groups treated with propofol 2×10−4 M (n=13) and isoflurane 1.5 vol% (n=10). *P= vs untreated group (n=21) (Kruskal–Wallis test followed by Scheffé's method).
British Journal of Anaesthesia  , DOI: ( /bja/aei077)
Copyright © 2005 British Journal of Anaesthesia Terms and Conditions

4. Fig 3
Relationship between the incidence of AD and anaesthetic concentration. Thiopental reduced the incidence of AD with increasing concentration (a), whereas all concentrations of propofol (b) and isoflurane (c) tested showed no change in the incidence of AD. *P<0.05 vs concentration of 10−4 M thiopental-treated group (Kruskal–Wallis test followed by Scheffé's method).
British Journal of Anaesthesia  , DOI: ( /bja/aei077)
Copyright © 2005 British Journal of Anaesthesia Terms and Conditions

5. Fig 4
Relationship between the degree of recovery from 3 min anoxia and the duration of AD in the untreated group. The degree of recovery is expressed as a percentage of the pre-anoxic control value. The straight line was fitted by the equation y=98.7–0.22x; R=0.55, P=0.03 (n=17).
British Journal of Anaesthesia  , DOI: ( /bja/aei077)
Copyright © 2005 British Journal of Anaesthesia Terms and Conditions