1. COMPARATIVE STUDY OF ADVERSE DONOR EVENTS IN VOLUNTARY AND REPLACEMENT WHOLE BLOOD DONORS: NEED OF ROBUST DONOR HEMOVIGILANCE PROGRAM
Dr Lubna Naseer, Dr Meena Sidhu
PG 3rd year
Govt. Medical college, Jammu

2. Background
Adverse Event was recognized as symptoms or signs of donor discomfort of sufficient severity such that either the donor called for attention of the staff or they were noticed by the staff.
Blood donation is safe, but small percentage of donors experience complications, mostly mild, that resolve promptly but are still unpleasant for donors, and blood services have an obligation to minimize them.
Adverse donor reactions can result in injury and decrease the likelihood of donor return. 

3. Aims and Objectives
The aim of this study was to compare the frequency and severity of AE’s in voluntary and replacement whole blood donors.

4. Material and Methods
Retrospective study of donor reactions documented at Department of IHBT Government Medical College, Jammu over a period of 1 year from April 2017 to March 2018.
Donors fulfilling national guidelines for blood donation were selected.
Phlebotomy was performed by trained personnel's.
Donors were observed during and following donation for 15 mints.
Blood donors were asked to report for any delayed adverse events after they have left the premises.

5. American Red Cross Hemovigilance Program classifies complications into defined categories
Pre syncopal - pallor, sweating or light headedness without loss of consciousness.
Syncopal complications are classified as;
Minor- if there is a transient loss of consciousness lasting less than one minute,
Major- prolonged loss of consciousness for more than a minute or complicated by loss of bowel/bladder control, seizures or convulsions
Local adverse events -include small haematomas (<25.8 mm2) or large(>25.8 mm2), bruises, infiltration, allergic reaction and a tingling sensation.

6. Results Table II: Showing reaction rate in Male and Female donors.
Category
No.
Reaction
Rate
p value
Total Donations
17527
641
3.65%
Replacement Donations
10763
424
3.93%
0.012
Voluntary Donations
6764
217
3.2%
Table 1: showing reaction rate in replacement and voluntary donors
Category
No.
Reaction
Rate
P Value
Total Male Donors
17011
606
3.6%
0.0001
Total Female Donors
516 35
6.8%
Table II: Showing reaction rate in Male and Female donors.

7. results Table III: Showing reaction rate in 1st time and repeat donors
Category
No.
Reaction
Rate
p Value
1st Time Male Donors
4422
461
10.53%
0.0001
1st Time Female Donors
155 21
Repeat Male Donors
12589
145
1.22%
Repeat Female Donors
361 14
Table III: Showing reaction rate in 1st time and repeat donors

8. Severity of Adverse Events

9. Types of Reaction

10. Symptoms of Vasovagal reaction

11. Donation site

12. Figure showing time of Reaction occurrence

13. Conclusion
The reaction rate was 3.65% , mostly Vasovagal type of reactions were most common ,seen more in females, first-time donors, replacement donors which is comparable with other studies.
So repeat, regular and voluntary donations should be encouraged
This study has increased our knowledge of risk factors associated with blood donation and provided an insight into the importance of voluntary donation and need to increase the same and highlighting the need for specific guidelines for the management of prone donor groups

14. THANK YOU